CDK13-related disorder - Wikipedia
CDK13-related disorder, also known as congenital heart defects, dysmorphic facial features and intellectual developmental disorder (CHDFIDD), is a very rare autosomal dominant genetic …
CDK13-Related Disorder - GeneReviews® - NCBI Bookshelf
2019年1月31日 · CDK13-related disorder, reported in 43 individuals to date, is characterized in all individuals by developmental delay / intellectual disability (DD/ID); nearly all individuals older …
CDK13 - Wikipedia
Cyclin dependent kinase 13 is an enzyme that in humans is encoded by the CDK13 gene. [5] [6] The protein encoded by this gene is a member of the cyclin-dependent serine/threonine …
CDK13 Gene - GeneCards | CDK13 Protein | CDK13 Antibody
2025年3月30日 · CDK13 (Cyclin Dependent Kinase 13) is a Protein Coding gene. Diseases associated with CDK13 include Congenital Heart Defects, Dysmorphic Facial Features, And …
CDK13相关疾病 - 维基百科，自由的百科全书
CDK13相关疾病 （英語： CDK13-related disorder），又称 先天性心脏病、面部异常及智力障碍相关疾病 （英語： Congenital heart defects, dysmorphic facial features and intellectual …
CDK13 phosphorylates the translation machinery and promotes
2023年3月7日 · Cyclin-dependent kinase 13 (CDK13) has been suggested to phosphorylate RNA polymerase II and is involved in transcriptional activation. However, whether CDK13 catalyzes …
Oncogenic CDK13 mutations impede nuclear RNA surveillance
RNA surveillance pathways detect and degrade defective transcripts to ensure RNA fidelity. We found that disrupted nuclear RNA surveillance is oncogenic. Cyclin-dependent kinase 13 …
cdk13蛋白分子量为 165 kda，主要定位于细胞核，并且多集中于存储 rna剪接因子的核斑中。现认为cdk13是核周区 （癌细胞中形成的亚核结构）的组成部分，核周区 的发生与恶性肿瘤的转 …
CDK13 cooperates with CDK12 to control global RNA …
Single inhibition of CDK12 or CDK13 induced transcriptional responses associated with cellular growth signaling pathways and/or DNA damage, with minimal effects on cell viability.
细胞周期蛋白依赖性激酶 13（CDK13）基因 | MCE
该基因编码的蛋白质是细胞周期蛋白依赖性丝氨酸/苏氨酸蛋白激酶家族的成员。 该家族的成员以其在细胞周期控制中作为主开关的重要作用而闻名。 这种蛋白质的确切功能尚未确定，但它 …