CDC6 - Wikipedia
Cell division control protein 6 homolog is a protein that in humans is encoded by the CDC6 gene. [5] [6] The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a …
Molecular Cancer︱山东大学齐鲁医院等团队揭示CDC6蛋白的去泛 …
细胞分裂周期蛋白6（CDC6）在DNA复制过程中发挥重要作用。作为前复制复合物（pre-RC）中的核心成员，如果CDC6发生突变或缺失，pre-RC将无法组装，DNA复制也会受到抑制。由 …
CDC6 Gene - GeneCards | CDC6 Protein | CDC6 Antibody
Dec 24, 2024 · CDC6 (Cell Division Cycle 6) is a Protein Coding gene. Diseases associated with CDC6 include Meier-Gorlin Syndrome 5 and Meier-Gorlin Syndrome 1. Among its related …
CDC6: from DNA replication to cell cycle checkpoints and …
Nov 28, 2007 · Cell division cycle 6 (CDC6) is an essential regulator of DNA replication in eukaryotic cells. Its best-characterized function is the assembly of prereplicative complexes at …
所有肿瘤都会发生异常的通路——Cell cycle信号通路（二） - 知乎
MCM、Cdc6、Cdt1、ORC等形成复制前复合物（pre-replication complex），又称为复制准许因子（replication license factor，RLF），激活后启动DNA复制。
The structure of ORC–Cdc6 on an origin DNA reveals the …
Jun 23, 2021 · The structure reveals that Cdc6 contributes to origin DNA recognition via its winged helix domain (WHD) and its initiator-specific motif.
细胞分裂周期 6（CDC6）基因 | MCE - MCE-生物活性分子大师
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early …
周期蛋白6在DNA复制、细胞周期检测点和肿瘤发生发展中的作用
周期蛋白6(cdc6)是组成前复制复合物(pre-rc)的主要蛋白之一,控制细胞从g1期进入s期,同时也参与激活和维持有丝分裂s-m期检测点机制.最近的研究发现其也具有原癌基因的特性,并在人多种 …
CDC6 regulates both G2/M transition and metaphase-to-anaphase ... - PubMed
Cell division cycle protein, CDC6, is essential for the initiation of DNA replication. CDC6 was recently shown to inhibit the microtubule-organizing activity of the centrosome. Here, we show …
去泛素化酶OTUD6A调控肿瘤演进新机制 - Pharmcube
Jun 5, 2024 · 细胞分裂周期蛋白6（Cell division cycle 6，CDC6）属于AAA+ATP酶家族成员，是DNA复制起始阶段的主要调控因子之一。CDC6不仅在DNA复制起始阶段发挥功能，而且 …