
CD58 - Wikipedia
CD58, lymphocyte-function antigen 3 (LFA-3), is a glycoprotein that plays a vital role in the body's immune response. The natural ligand to CD58, CD2, is most commonly found on the surfaces …
廖泉等关于CD58免疫生物学概述的研究发表于Q1杂志 - 知乎
糖蛋白CD58,又称 淋巴细胞功能抗原3 (lymphocyte-function antigen 3, LFA-3),是一种广泛分布于人体组织和细胞上的共刺激受体。其天然配体CD2主要表达于T/NK细胞表面。
CD58分子(CD58)|ELISA指标 - 百家号
cd58,即淋巴细胞功能相关抗原3(lfa-3),是一种在抗原呈递细胞(apc)上表达的细胞粘附分子,特别是巨噬细胞。它与t细胞上的cd2(lfa-2)结合,对加强t细胞和专业抗原呈递细胞之间的 …
The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and …
2023年6月15日 · We show that intact cancer cell CD58 expression is required for effective T cell-mediated anti-tumor responses, and that loss of CD58 confers cancer immune evasion …
Cancer research:张会来教授团队揭示CD58基因变异调控抗肿瘤 …
2024年5月4日 · cd58作为一种重要免疫调控分子,其受体cd2通常表达在t或nk细胞表面,cd58与cd2结合在维持肿瘤微环境中t或nk细胞活化和抗肿瘤免疫应答过程发挥重要作用。
CD58 Gene - GeneCards | LFA3 Protein | LFA3 Antibody
2025年3月28日 · CD58 (CD58 Molecule) is a Protein Coding gene. Diseases associated with CD58 include Hematologic Cancer and Paroxysmal Nocturnal Hemoglobinuria. Among its …
CD58 Immunobiology at a Glance - PMC - PubMed Central (PMC)
In particular, the CD2-CD58 interaction is involved in the regulation of antiviral responses, inflammatory responses in autoimmune diseases, immune rejection of transplantation, and …
CD58 Immunobiology at a Glance - Frontiers
2021年6月7日 · Herein, we have comprehensively summarized CD58 isoforms, sCD58, CD2-CD58 interaction, their structure and function, IS formation, CD58 polymorphisms, meanwhile …
CD58缺失导致肿瘤免疫逃逸的多重机制 - 网易
2023年7月2日 · 利用黑色素瘤患者的单细胞RNA测序(scRNA-seq)和患者模型的功能筛选,研究人员发现癌细胞可自主下调CD58(也称为淋巴细胞粘附因子3,LFA-3),与其ICB抵抗和T细 …
The CD58–CD2 axis in cancer immune evasion - Nature
2022年5月19日 · A preprint by Ho et al. investigates the role of decreased CD58 expression in cancer cell immune evasion, through both lack of T cell co-stimulation and increased T cell …