CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene. [5] …

CD46为一单链跨膜糖蛋白，其染色体定位于人类1号染色体短臂的32号区，分子量为45-70kDa，又命名为gp45-70，属于补体活化调节蛋白因子家族。CD46的N端由四个补体控制蛋 …

2025年3月28日 · CD46 (CD46 Molecule) is a Protein Coding gene. Diseases associated with CD46 include Hemolytic Uremic Syndrome, Atypical 2 and Genetic Atypical Hemolytic-Uremic …

Membrane cofactor protein (MCP; CD46) is a type one transmembrane complement regulatory protein expressed by almost every cell type (with the noteworthy exception of erythrocytes) …

cd46 分子： 该基因编码的蛋白质是 i 型膜蛋白，是补体系统的调节部分。 编码的蛋白质具有辅助因子活性，可通过血清因子 I 使补体成分 C3b 和 C4b 失活，从而保护宿主细胞免受补体损伤。

CD46 为一种单链跨膜糖蛋白，属于补体活化调节蛋白因子家族。 CD46在细胞表面分布很广，大多数正常细胞上都有CD46表达，包括造血细胞系、成纤维细胞、表皮细胞、内皮细胞及星状 …

CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b …

In the last 10 years, the human cell-surface molecule, CD46, has evolved from 'just another complement regulator' to a receptor for a striking array of pathogens. CD46 not only protects …

In particular, the complement regulator CD46 emerges as a key sensor of immune activation and a vital modulator of adaptive immunity. In this review, we summarize the current knowledge of …

5 天之前 · cd46是一种在多种恶性肿瘤细胞表面高度表达的分子，转移性去势抵抗性前列腺癌如果表达cd46则往往代表肿瘤有侵袭性和预后不良，因此针对cd46开发 ...