
022071 - CD4Cre Strain Details - The Jackson Laboratory
For more information on these RFID chips, including our FAQ, please visit our Mouse Identification page . CD4-Cre transgenic mice contain CD4 enhancer, promoter and silencer …
Efficient CD4-Cre mediated conditional KRas expression in alveolar ...
We propose that caKRas-CD4Cre mice represent a novel model of proliferative pneumonia involving macrophages and epithelial cells, and that the CD4Cre model may offer unique utility …
Immunologic Applications of Conditional Gene Modification …
CD4-Cre deletes floxed sequences in both CD4 and CD8 T cells. To delete floxed genes only in peripheral CD8 but not CD4 T cells, CD8a–Cre (Maekawa et al., 2008), also known as …
022356 - CD4CreER[T2] Strain Details - The Jackson Laboratory
022356 B6(129X1)-Tg(Cd4-cre/ERT2)11Gnri/J This CD4CreER T2 mutant mouse strain, carrying a transgene with tamoxifen-inducible Cre recombinase under the control of the mouse Cd4 …
Chromosomal localisation of the CD4cre transgene in B6·Cg-Tg(Cd4-cre …
2016年9月1日 · Here we describe a dose-dependent effect of continued CRE recombinase expression on CD4 + T cell numbers and frequencies in the spleen, provide the location of the …
Cd4-cre Transgenic | Taconic Biosciences
The CD4-Cre Microinjected Mouse uses the mouse Cd4 promoter/enhancer/silencer, which first allows expression of CD4 as thymocytes enter the double positive stage. The silencer region …
A Cre-driven allele-conditioning line to interrogate CD4
2021年10月12日 · In the CD4 Cre line, Cre recombinase is under the control of the Cd4 enhancer, promoter, and silencer, and results in Cre-mediated targeting in all T cell …
For example, anecdotal evidence from the cross of CD4-Cre with the Cre-inducible LSL-EYFP fluorescent reporter Rosa26 re-vealed a near-complete recombination in plasmacytoid …
A Cre-driven allele-conditioning line to interrogate CD4 - Cell …
2021年10月12日 · Using an allele-conditioning strategy, Andrews et al. generate murine lines that temporally restrict Cre activity and gene deletion to CD4+ T conventional cells, while sparing …
Generation of CD4CreERT2 transgenic mice to study development …
To study molecular mechanisms of peripheral CD4-T-cell differentiation in-vivo and in-vitro we generated transgenic mice expressing a tamoxifen inducible Cre recombinase (CreER T2) …
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