The mannose receptor (Cluster of Differentiation 206, CD206) is a C-type lectin primarily present on the surface of macrophages, immature dendritic cells and liver sinusoidal endothelial cells, …

CD206 expression reflects variation in M2 macrophage abundance and is more highly expressed in AML patients than normal controls. (a) mRNA levels of M2 marker genes (CD68, CD163, …

2017年8月18日 · CD206 is a specific marker for M2-like ATMs. To investigate the involvement of M2-like ATMs in the regulation of adipose tissue dynamics during metabolism-associated …

The relevance of RP-182 for targeting the mannose receptor CD206 on CD206 high M2-like macrophages, including CD206 high TAMs, was tested in human and murine macrophage …

2022年11月21日 · Depletion of CD206 + M2-like MΦ promotes myogenesis. First, we performed a time course experiment to examine sequential events during the recovery process (Fig. …

The macrophage mannose receptor (MR, CD206) is a C-type lectin expressed predominantly by most tissue macrophages, dendritic cells and specific lymphatic or endothelial cells. It …

2019年11月3日 · High CD206 expression predicted inferior overall survival (OS) and event-free survival (EFS) in two independent AML cohorts. Among 175 patients with intermediate-risk …

2019年12月10日 · CD206, a mannose receptor, is mainly expressed on the surface of alternatively activated macrophages where it acts as a pattern recognition receptor and plays …

CD206 expression status as a surrogate for M2 macrophage population varied considerably across clinical pancreatic cancer resection specimens (Fig. 5A and fig. S23A). CD206 was …

2024年11月27日 · CD206 is a common marker of a putative immunosuppressive "M2" state in tumor-associated macrophages (TAMs). We made a novel conditional CD206 (Mrc1) knock-in …