City Hall Office: 200 N. Spring St., Rm. 475 Los Angeles, CA 90012 Phone: 213.473.7015 Fax: 213.626.5431

City Hall Office: 200 N. Spring St., Rm. 475 Los Angeles, CA 90012 Phone: 213.473.7015 Fax: 213.626.5431

2008年10月19日 · The glycan determinant CD15 (also known as Lewis x, or Lex) is a distinguishing marker for human myeloid cells and mediates neutrophil adhesion to dendritic cells.

CD15 is present on almost all Reed–Sternberg cells, including their rare mononuclear variants, and, as such, can be used in immunohistochemistry to identify the presence of such cells in biopsies. The presence of these cells is diagnostic of Hodgkin's lymphoma.

CD15, the X hapten or Lewis X antigen, can be identified with the LeuM1 antibody. Originally noted as a monocyte/myeloid cell marker, it was recognized as a marker for the Reed-Sternberg cells of classical Hodgkin lymphoma.

CD15 (3-fucosyl-N-acetyl-lactosamine) is a cluster of differentiation antigen – an immunologically significant molecule. CD15 is a carbohydrate adhesion molecule (1) that can be expressed on glycoproteins, glycolipids and proteoglycans.

The glycan determinant Lewis x (Lex/CD15) is a distinguishing marker for human myeloid cells and mediates neutrophil adhesion to dendritic cells. Despite broad interest in this structure, the mechanism(s) underlying Lex/CD15 expression remain ...

The glycan determinant CD15 (also known as Lewis x, or Le(x)) is a distinguishing marker for human myeloid cells and mediates neutrophil adhesion to dendritic cells. Despite broad interest in this structure, the mechanisms underlying CD15 expression remain relatively uncharacterized.

2022年4月28日 · CD15 (Lewis X/Lex) is a fucosyl (3-fucosly-N-acetyl-lactosamine) moiety found on membrane proteins of various cancer cells. These cancers include renal cancer, prostate and bladder cancers, acute leukaemias, hepatocellular carcinoma, breast cancer and melanoma.

CD15 is a haemopoietic differentiation antigen expressed on most terminally differentiated myeloid cells including granulocytes, eosinophils, mast cells, monocytes/macrophages, and Langerhans’ cells.