Integrin, alpha E (ITGAE) also known as CD103 (cluster of differentiation 103) is an integrin protein that in human is encoded by the ITGAE gene. [5] [6] CD103 binds integrin beta 7 (β7– …

2023年5月31日 · cd69和cd103：一般认为cd103+ cd8+代表真正的trm原亚群特征。 人和小鼠肺trm均表达cd69。 部分表达cd103和/或cd49a，分别通过与细胞外基质中的上皮e-钙粘蛋白和 …

2019年3月7日 · CD103 is a transmembrane heterodimer complex that mediates cell adhesion, migration, and lymphocyte homing of cell through interaction with E-cadherin. Recently, …

2018年7月13日 · CD103 + CD39 + CD8 TILs have a distinct T-cell receptor (TCR) repertoire, with T-cell clones expanded in the tumor but present at low frequencies in the periphery. CD103 + …

2011年11月15日 · Here we show that CD103, an integrin mediating lymphocyte retention in epithelial tissues, is expressed at high levels on tumor-infiltrating FoxP3+ Treg in several types …

2019年10月7日 · We found that CD69 hi CD103 lo CD4 + T RM cells produced effector cytokines and promoted the inflammation and fibrotic responses induced by chronic exposure to …

2021年6月21日 · Integrin CD103 mediates the adhesion and tissue retention of T cells by binding to E-cadherin which is abundant on epithelial cells. Notably, CD103 is highly expressed on …

cd103+trm在实体瘤的免疫监视以及限制肿瘤生长中起着重要作用。 研究表明，在接受标准治疗的癌症患者中，该类细胞的肿瘤浸润与更好的临床结果相关。

CD103 is largely implicated for its role in the homing and retention of lymphocytes in peripheral tissues (9–13) with less focus on the biological contribution of CD103 ligation beyond …

2011年1月4日 · Here we show that CD103, an integrin mediating lymphocyte retention in epithelial tissues, is expressed at high levels on tumor-infiltrating FoxP3+ Treg in several types …