CCL27 is associated with homing of memory T lymphocytes to the skin, and plays a role in T cell-mediated inflammation of the skin. [6] [7] CCL27 is expressed in numerous tissues, including …

CCL27 (also called ESkine, ALP, ILC, or CTACK) is a chemokine predominantly expressed by skin keratinocytes (Baird et al., 1999; Homey et al., 2000b; Hromas et al., 1999; Ishikawa …

2022年5月18日 · Beyond the skin, CCL27-knockout mice have increased infiltration of CCR10 + T cells into lungs and reproductive tracts, the latter of which also exhibit spontaneous …

2025年3月30日 · CCL27 (C-C Motif Chemokine Ligand 27) is a Protein Coding gene. Diseases associated with CCL27 include Melanoma and Molluscum Contagiosum . Among its related …

2025年2月8日 · CCL27 drives baseline recruitment of Herpes simplex virus-specific CD8 T cells expressing CCR10, while interferon-responsive CXCR3 ligands recruit additional cells in …

2002年2月1日 · The skin-associated chemokine CCL27 (also called CTACK, ALP and ESkine) and its receptor CCR10 (GPR-2) mediate chemotactic responses of skin-homing T cells in vitro.

Moreover, several studies have shown an association between CCL27 expression and a variety of neoplasms including skin cancer.In this chapter, we address the role of chemokine CCL27 in …

Our findings demon-strate that CCL27 is critical for immune homeostasis across barrier tissues. Barrier tissues, including the skin and mucosa, harbor a diverse complement of immune cells. …

Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10. Gene Ontology (GO) …

We report here that psoriasis-associated suppression of CCL27/CCR10-derived immune regulatory signals contributes to enhanced IL-17A/IL-22-producing skin T cell over-activation …