Historically, the [2]catenane was prepared by statistical threading in extremely low yield (< 1%) by Wasserman. 1 Schill and Lüttringhaus improved the yield through a covalent bond-directed synthesis approach; however, the sheer length of the procedure largely restricted its application to academic curiosities. 2 Taking inspiration from weak ...

Template-mediated synthesis of [2]catenane was reported by Sauvage et al. in 1983. 7 The preferential tetrahedral coordination geometry of copper(I) was utilized in the binding of two phenanthroline (phen) moieties in an orthogonal fashion, leading to the threading of the 2,9-diphenyl-1,10-phenanthroline (dpp) ligand 2 through macrocycle 1 as shown in Scheme 1.

Linear and branched oligocatenanes ranging from [3]- to [7]catenane <1997AGE2070, 1998JA4295, 2000EJO1121>, including [5]catenane 167, known as olympiadane <1994AGE1286>, were also synthesized and characterized by X-ray analyses. The number of interlocked macrocycles within each catenane could also …

2023年6月8日 · In 1960, Edel Wasserman published what he believed to be the first synthesis of an interlocked molecule—a [2]catenane—in the Journal of the American Chemical Society. 4 This work received considerable attention because it represented the first experimental realization of a mechanical bond in interlocked molecules, which had been hypothesized as early as 1912. 5 Wasserman’s approach ...

2024年1月17日 · Although chemists have pursued extended linear poly[n]catenane architectures for many decades, there still exists a fundamental gap between the synthesis of well-defined, linear oligomers and that of disperse polymers that are often produced as a mixture of architectures. Here, we report two convergent one-pot syntheses that “zip-tie ...

The structural information displayed by 1 H NMR and by X-ray studies is in perfect agreement. Figure 5 represents the first X-ray structures of a metallo [2] catenane (Figure 5a) and a free [2]catenane (Figure 5b). 19 The interlocking of the two macrocycles in …

2003年3月21日 · Similar to the original catenane, p53cat tet, there was a noticeable increase in the mean residue molar ellipticity between the catenane and the linear analogue at 4 °C, although there was an overall decrease in the mean residue molar ellipticity for both sequences compared to the tetramer-based sequences.

2021年1月10日 · To prepare the recombinant proteins for catenane construction, three different plasmids harboring MhIHL-V54L, Cat1-MhIHL-V54L, and Cat2-MhIHL-V54L were transformed into E. coli BL21 and induced by IPTG. SDS-PAGE analysis was carried out to monitor the expression and assembling of the protein catenanes.

2024年3月15日 · After the simple purification of each step, the 1 H NMR of hexameric helicate 2, metallated Star of David [2]catenane 3, and organic Star of David [2]catenane 4 are shown in Figures 11, 12, and 13 and 14, respectively, and the low-resolution ESI-MS of hexameric helicate 2, metallated Star of David [2]catenane 3, and organic Star of David [2 ...

1996年3月1日 · This article reviews the recent progress of catenane synthesis. A focus is self-assembled catenanes containing transition metals in their backbones. Treatment of a cis -protected Pd(II) complex with a pyridine-based simple ligand gave rise to the self-assembly of an equilibrium mixture of a Pd(II)-linked catenane and its component ring.