Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and …

Carbapenems are a class of very effective antibiotic agents most commonly used for treatment of severe bacterial infections. This class of antibiotics is usually reserved for known or suspected …

2011年8月22日 · In this review, we summarize the current “state of the art” of carbapenem antibiotics and their role in our antimicrobial armamentarium. Among the β-lactams currently …

2020年8月4日 · Meropenem is a carbapenem antibiotic for parenteral use that exerts its action by interfering with bacterial wall synthesis. It penetrates the bacterial cell wall with its high levels …

Carbapenems inhibit the penicillin-binding-protein (PBP) family of enzymes by acylating the targets. Carbapenem affinity for the different PBPs varies between bacteria, and Gram …

2016年2月26日 · Carbapenems are often considered to have the broadest spectrum of activity among all antibiotic classes. Closely related to penicillins, carbapenems are bactericidal beta …

Inhibits cell wall synthesis and causes cell lysis. Study with Quizlet and memorize flashcards containing terms like Carbapenem MOA and AE, Imipenem/cilastin (IV) Meropenem (IV) …

Study with Quizlet and memorize flashcards containing terms like carbapenem structure, carbapenem moa, carbapenem properties and more.

Study with Quizlet and memorize flashcards containing terms like What is the carbapenem MOA?, What do carbapenems cover? Exceptions?, What are the carbapenems? and more.

Imipenem and meropenem, members of the carbapenem class of β-lactam antibiotics, are among the most broadly active antibiotics available for systemic use in humans.