CAELYX 英文名称：Doxorubicin Hydrochloride Liposome Injection . 汉语拼音：Yansuan Duoroubixing Zhizhiti Zhusheye 【成份】 活性成份：盐酸多柔比星. 化学名称：(1S,3S)-3-乙醇酰-1,2,3,4,6,11-六氧-3,5,12-三羟基-10-甲氧基-6,13-二氧并四苯-1-基-3-氨基-2,3,6-三去氧-α-L-来苏吡喃糖苷. 化学结构 ...

Caelyx is concentrate to be made up into a solution for infusion (drip into a vein). It contains the active substance doxorubicin hydrochloride (2 mg/ml). What is Caelyx used for? Caelyx is used to treat the following types of cancer in adults: metastatic breast …

2021年5月27日 · Caelyx (pegylated liposomal doxorubicin hydrochloride for injection) is an anthracycline topoisomerase II inhibitor indicated for monotherapy for patients with metastatic breast cancer, where there is an increased cardiac risk associated with conventional doxorubicin; advanced ovarian carcinoma in women who have failed standard first-line therap...

Caelyx® is a new treatment for advanced ovarian cancer, which delivers doxorubicin encapsulated in long-circulating Stealth® liposomes, resulting in a prolonged circulation and enhanced tumour targeting of the drug, together with a markedly different safety profile compared with native doxorubicin.

Caelyx pegylated liposomal is doxorubicin hydrochloride encapsulated in liposomes with surface-bound methoxypolyethylene glycol (MPEG). This process is known as pegylation and protects liposomes from detection by the mononuclear phagocyte system (MPS), which …

2019年10月11日 · Caelyx pegylated liposomal is a medicine used to treat the following types of cancer in adults: metastatic breast cancer in patients at risk of heart problems. ‘Metastatic’ means the cancer has spread to other parts of the body. Caelyx pegylated liposomal is …

CAELYX (Pegylated Liposomal Doxorubicin Hydrochloride for Injection) exhibits unique pharmacokinetic properties and must not be used interchangeably with other formulations of doxorubicin hydrochloride. Health Canada has not authorized an indication for pediatric use.

2020年8月6日 · CAELYX是一种脂质体制剂，系将盐酸多柔比星通过与甲氧基聚乙二醇的表面结合包封于脂质体中。 这种工艺被称作为空间稳定或隐匿，可以保护脂质体免受单核巨噬细胞系统 (MPS)识别，从而延长其在血液循环中的时间。 用于治疗低CD4 (<200 CD4淋巴细胞/mm3)及有广泛皮肤粘膜内脏疾病或内脏疾病患者的艾滋病相关卡波西肉瘤 (AIDS-KS)。 可用作AIDSKS患者的一线全身化疗或二线化疗，AIDSKS患者患有已发生的疾病或对以下药物的先前联合全身化疗 …

Caelyx is a new treatment for advanced ovarian cancer, which delivers doxorubicin encapsulated in long-circulating Stealth liposomes, resulting in a prolonged circulation and enhanced tumour targeting of the drug, together with a markedly different safety …

Pegylated liposomal doxorubicin (Caelyx ®) is used to treat breast cancer, ovarian cancer, myeloma, and HIV-related Kaposi’s sarcoma. It may sometimes be used to treat other cancers. It is best to read this information with our general information about chemotherapy and the type of cancer you have.