Cytochrome P450 2E1 (abbreviated CYP2E1, EC 1.14.13.n7) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the …

2024年12月24日 · CYP2E1 (Cytochrome P450 Family 2 Subfamily E Member 1) is a Protein Coding gene. Diseases associated with CYP2E1 include Alcoholic Liver Cirrhosis and Alcohol …

Besides the detoxifying role of CYP2E1 for compounds such as electrophilic agents, reactive oxygen species, free radical products, and the bioactivation of xenobiotics, CYP2E1 is also …

Cytochrome P450 2E1 (CYP2E1) may be a key pathway in generating oxidative stress, nitrosative stress, lipid peroxidation, and causing alcoholic liver injury by various hepatotoxins. It was...

cyp2e1是肝内 三氯乙烯 、 氟烷 、安氟醚、七氟醚代谢的重要酶。 约5%的七氟醚可很快代谢为 氟化物 和hexafluoro isopropanol (HFIP)，再被 糖醛酸 化后经尿排泄。

P450 2E1 is also involved in the bioactivation of a number of low molecular weight cancer suspects, as validated in vivo in mouse models where cancers could be attenuated by deletion …

This study presents a timely systematic review on CYP2E1's xenobiotic metabolism, genetic polymorphism, and inhibitors, with the focus on their clinical relevance for the efficacy and …

CYP2E1 has a non-hyperbolic kinetic profile that cannot be explained by the common Michaelis-Menten mechanism. Further studies show that the non-hyperbolic kinetic behaviors are …

cyp2e1还是有效的活性氧生成物，例如超氧阴离子自由基和过氧化氢，在铁催化剂存在下，cyp2e1会产生强力氧化剂，例如羟基自由基。 这篇综述文章总结了CYP2E1的一些生化和 …

关于 cyp2e1 Cytogenetic location: 10q26.3 Genomic coordinates (GRCh38): 10:133,527,363-133,539,123 (from NCBI) This gene has 10 transcripts (splice variants), 93 orthologues and 15 …