CYP17A1 is a 57.4 kDa protein that belongs to the cytochrome P450 family. [10][11] The protein encoded by its cDNA is composed of 508 amino acid residues. As an enzyme, CYP17A1 …

细胞色素 P450 17A1 （英語： Cytochrome P450 17A1）也被称为 甾体17α-单加氧酶 （steroid 17α-monooxygenase）， 17α-羟基化酶 （17α-hydroxylase）， 17,20-碳链裂解酶 （17,20 …

2025年3月30日 · CYP17A1 (Cytochrome P450 Family 17 Subfamily A Member 1) is a Protein Coding gene. Diseases associated with CYP17A1 include Adrenal Hyperplasia, Congenital, …

Cytochrome P450 17A1 (CYP17A1; also P450c17and P450sccII) is a critically important enzyme in humans that catalyzes the formation of all endogenous androgens. It is an atypical …

2021年5月15日 · Cytochrome P450 17A1 (CYP17A1) is a critical steroidogenic enzyme, essential for producing glucocorticoids and sex hormones. This review discusses the complex activity of …

该基因编码细胞色素 P450 酶超家族的成员。 细胞色素 P450 蛋白是单加氧酶，可催化许多涉及药物代谢和胆固醇、类固醇和其他脂质合成的反应。 该蛋白质定位于内质网。 它同时具有 17α- …

The CYP17A1 gene provides instructions for making a member of the cytochrome P450 enzyme family. Like other cytochrome P450 enzymes, CYP17A1 is involved in the formation …

21-羟化酶缺乏症（21-OHD）为CAH最常见的病因，占CAH的90%~95%，本文报道CAH属17α-羟化酶缺乏症（17-OHD），该种类极为罕见，约占CAH的1%。 由于17-OHD患者早期可无典型 …

2020年1月17日 · CYP17A1, also known as the 17α-hydroxylase and 17/20 lyase enzyme (P450 17α), is considered essential in the pathway of steroid biosynthesis (especially androgens and …

2021年3月3日 · HGNC Approved Gene Symbol: CYP17A1. Cytogenetic location: 10q24.32 Genomic coordinates (GRCh38) : 10:102,830,531-102,837,413 (from NCBI) The CYP17 gene …