2025年3月30日 · CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1) is a Protein Coding gene. Diseases associated with CYFIP1 include Autism Spectrum Disorder and Fragile X Syndrome. …

Cytoplasmic FMR1-interacting protein 1 is a protein that in humans is encoded by the CYFIP1 gene. [5][6]

2025年1月4日 · Study found that Cyfip1, a subunit of the WAVE complex, which regulates cytoskeletal dynamics, is commonly deleted in human epithelial cancers. This gene encodes a …

2021年8月21日 · CYFIP1, similar to CYFIP2, acts in the WAVE regulatory complex (WRC) and plays a role in actin dynamics through the activation of the Arp2/3 complex and in a …

该基因编码一种调节细胞骨架动力学和蛋白质翻译的蛋白质。 编码的蛋白质是 WAVE 调节复合物 (WRC) 的一个组成部分，它促进肌动蛋白聚合。 该蛋白还与突触功能调节因子 FMR1 蛋白和翻 …

2019年8月1日 · Copy-number variants of the CYFIP1 gene in humans have been linked to autism spectrum disorders (ASD) and schizophrenia (SCZ), two neuropsychiatric disorders …

Here, we show that brain-derived neurotrophic factor (BDNF)-driven synaptic signaling releases CYFIP1 from the translational inhibitory complex, triggering translation of target mRNAs and …

2021年7月29日 · CYFIP1, similar to CYFIP2, acts in the WAVE regulatory complex (WRC) and plays a role in actin dynamics through the activation of the Arp2/3 complex and in a …

总 结 该研究阐述了 CYFIP1的异常水平是如何导致在生化、突触和行为水平上出现与精神分裂症和自闭症谱系障碍相关的常见且独特的缺陷。 研究确定了一组 与CYFIP1相互作用的新型mRNA …

2025年1月4日 · Cyfip1 is downregulated in acute lymphoblastic leukemia and may be a potential biomarker in acute lymphoblastic leukemia. Reduced CYFIP1 in Human Neural Progenitors …