The chemokine (C-X-C motif) ligand 1 (CXCL1) is a small peptide belonging to the CXC chemokine family that acts as a chemoattractant for several immune cells, especially neutrophils [5] [6] or other non-hematopoietic cells to the site of injury or infection and plays an important role in regulation of immune and inflammatory responses. It was ...

2025年3月30日 · CXCL1 (C-X-C Motif Chemokine Ligand 1) is a Protein Coding gene. Diseases associated with CXCL1 include Tonsillitis and Bacterial Meningitis . Among its related pathways are MIF Mediated Glucocorticoid Regulation and GPCR downstream signalling .

2023年7月1日 · CXCL1, known as growth related oncogene, can be expressed in many immune cells and neurons. The main function of CXCL1 is recruitment of immunocytes, especially neutrophils . It can promote...

2022年1月12日 · CXCL1 is one of the most important chemokines, part of a group of chemotactic cytokines involved in the development of many inflammatory diseases. It activates CXCR2 and, at high levels, CXCR1.

2023年4月10日 · Here, we explored the protumor effects of CXCL1, a commonly elevated inflammatory chemokine in cirrhosis, in HCC. The protumor role was confirmed in clinical samples from HCC patients.

This review describes the role of CXCL1, a chemokine crucial in inflammation as a chemoattractant for neutrophils, in physiology and in selected major non-cancer diseases. Due to the vast amount of available information, we focus on the role CXCL1 ...

CXCL1 and Its Specific Receptor in Colorectal Cancer. A growing body of evidence indicates that CXCL1 promotes chemoattraction, wound healing and angiogenesis.