Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein …

2023年4月27日 · F4/80 （EMR1）多用于标记成熟小鼠巨噬细胞，在巨噬细胞的成熟和活化过程中表达变化明显，参与细胞黏附，并可能参与专门涉及免疫系统细胞的细胞间相互作用。 …

2025年3月30日 · CSF1R (Colony Stimulating Factor 1 Receptor) is a Protein Coding gene. Diseases associated with CSF1R include Leukoencephalopathy, Hereditary Diffuse, With …

2022年9月13日 · CSF-1R信号通路 集落刺激因子-1（CSF-1），也称巨噬细胞集落刺激因子，是导致各种炎症性疾病的最常见的促炎细胞因子之一。 其在骨关节炎、癌症和其他自身免疫性疾 …

The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/ PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated …

2012年8月30日 · The diagnosis of CSF1R-related disorder is established in a proband with suggestive findings and a heterozygous CSF1R pathogenic variant or biallelic CSF1R …

2025年3月26日 · Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase …

2023年1月5日 · Colony-Stimulating Factor-1 Receptor (CSF1R) is a receptor tyrosine kinase that controls the differentiation and maintenance of most tissue-resident macrophages and bone …

2025年2月8日 · Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor …

2020年10月23日 · Colony-stimulating factor-1 receptor (CSF1R) and its ligand CSF1 are elevated in CNS tissue derived from MS patients. We performed a large-scale RNA-sequencing …