
Congenital Cytomegalovirus Infection: Update on Diagnosis and …
CCMV infection is the leading non-genetic cause of SNHL in children across studies. Among infants who develop CMV-related SNHL, hearing loss may be present at birth or may have delayed onset, occurring throughout the first several years of life.
Universal newborn screening for congenital cytomegalovirus …
Early identification of congenital CMV allows for interventions such as antiviral therapy (when indicated) and enables anticipatory audiological monitoring that facilitates timely detection of delayed-onset SNHL. However, there are debates about …
Universal newborn screening for congenital cytomegalovirus …
Congenital cytomegalovirus (CMV) infection is the leading infectious cause of childhood disability, in particular sensorineural hearing loss (SNHL). Timeliness of diagnosis is crucial, since the presence of CMV in any compartment (eg, blood, urine, or saliva) after age 21 days can mean postnatal acq …
Update on congenital cytomegalovirus infection: Prenatal prevention ...
2020年9月16日 · Cytomegalovirus (CMV) is the leading cause of congenital infection and the most common cause of non-genetic sensorineural hearing loss (SNHL) in childhood. Although most infected infants are asymptomatic at birth, the risk for SNHL and other neurodevelopmental morbidity makes congenital CMV (cCMV) a …
Congenital cytomegalovirus: what the otolaryngologist should …
Congenital CMV is an unrecognized cause of SNHL that all otolaryngologists should be aware of as it represents the only treatable cause of congenital SNHL. Recent findings: The current review highlights the recent advances on congenital CMV, including methods of diagnosis and prevention of progression of hearing loss with valganciclovir treatment.
Congenital Cytomegalovirus Infection as a Cause of Sensorineural ...
The burden of CMV-associated sensorineural hearing loss (SNHL) in populations with CMV seroprevalence approaching 100% is unknown. The purpose of this study was to assess the rate, associated factors and predictors of SNHL in CMV-infected infants identified by newborn screening in a highly seropositive maternal population.
Cytomegalovirus: A Major Cause of Hearing Loss in Children
Dollard et al. (2007) report a weighted average of sensorineural hearing loss (SNHL) of 14.1% due to congenital CMV infection. Fowler and Boppana (2006) reported hearing loss in 8.7% of children with asymptomatic infections and in 41% with symptomatic infections.
What to Know About Advances in CMV Detection, Prevention:
CMV-related sensorineural hearing loss (SNHL) is second only to genetic causes of hearing loss both at birth and during the early years of life. SNHL following congenital CMV may be present at birth or occur later (late onset) in childhood and early adolescence.
Management of Congenital Cytomegalovirus-Related Hearing Loss
2020年5月29日 · The aim of this report is to review the current literature regarding the diagnosis, treatment, management, and rehabilitation of congenital cytomegalovirus (cCMV)–associated sensorineural hearing loss (SNHL). Hearing-targeted CMV screening is successful in identifying cases of cCMV-related hearing loss.
A Review of Sensorineural Hearing Loss in Congenital …
Vertical transmission of HCMV, that is via the placenta from infected mother to fetus, is one of the leading causes of congenital sensorineural hearing loss (SNHL) and neurodevelopmental complications in newborns. It accounts for up to 10% of SNHL cases in newborns, of both unilateral and bilateral types.
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