2023年1月23日 · Thiazide diuretics are first-line drugs for the treatment of hypertension, but hypertension treatment guidelines have systematically discouraged their use in patients with …

Our objective is to systematically assess the benefits and harms of diuretics for people at all stages of CKD. Chronic kidney disease (CKD) is a worldwide public health problem and has …

We review the updated guidelines on thiazide use in advanced CKD, the antihypertensive mechanism of thiazides, and the clinical studies of thiazides in CKD.

2023年11月12日 · Hydrochlorothiazide is a thiazide-type diuretic that inhibits sodium resorption in the distal convoluted tubules of the kidney. Thiazides, a reliable class of antihypertensive …

To evaluate the effects of diuretics on CKD-MBD, we have performed a prospective randomized trial comparing hydrochlorothiazide with furosemide in a stage 3CKD population followed for 1 …

Up to 92% of patients with chronic kidney disease (CKD) have comorbid hypertension, which is associated with increased cardiovascular risk, morbidity, and mortality . Extracellular volume …

2021年9月15日 · Hypertension is nearly ubiquitous in individuals with chronic kidney disease (CKD), with a prevalence of more than 80%, including more than 50% requiring 3 or more …

2022年10月7日 · In summary, substantial evidence indicates that chlorthalidone should be the preferred thiazide-type diuretic in people with hypertension (Figure). It is long-acting, 3× as …

2020年1月21日 · There is some evidence that patients with CKD and uncontrolled hypertension while taking renin-angiotensin system inhibitors may see renal benefits from adding HCTZ, but …

Chronic kidney disease (CKD) is both a common cause of hypertension and CKD is also a complication of uncontrolled hypertension. The interaction between hypertension and CKD is …