
Pathology Outlines - Cytokeratin 7 (CK7, K7)
CK7- / CK20+: Colorectal carcinoma (particularly early stage) (Hum Pathol 2005;36:275) Merkel cell carcinoma (88% CK20+ with a perinuclear punctate or dot-like pattern, 23% CK7+) (Appl …
Pathology Outlines - Clear cell
2024年5月2日 · Comment: Tumor cells show positive immunostaining for PAX8, CAIX and keratin CAM 5.2. CK7 is negative arguing against clear cell papillary renal cell tumor. Kidney, radical …
Pathology Outlines - Clear cell papillary renal cell tumor
2022年11月21日 · Also has diffuse CAIX but is positive for CD10 and negative or focal for CK7; Loss of chromosome 3p commonly seen Papillary renal cell carcinoma: Clear glycogenated …
Pathology Outlines - Small cell carcinoma
2022年9月20日 · D. INSM1+, chromogranin+, CK7- punctate, p40-, Ki67 high. The tumor shown is small cell carcinoma of the lung. Of the choices listed, INSM1+, chromogranin+, CK7- …
Pathology Outlines - Cutaneous adnexal NUT carcinoma
2024年10月8日 · Luminal cells are positive for CK7 Basal cells are positive for p40, p63 and CK5 Defined by identifying NUTM1 or NUTM2B fusions with BRD4 interacting partners (i.e., BRD3, …
Pathology Outlines - High grade serous carcinoma
The tumor cells are positive for CK7 and PAX8 with abnormal (overexpression) of p53 but negative for CK20. Estrogen receptor and progesterone receptor expression is negative. …
Pathology Outlines - Stains & CD markers
Cervix: CEA CK7 estrogen receptor (ER) GATA3 HIK1086 HPV Ki67 MUC6 p16 p40 p53 p63 PAX8 progesterone receptor (PR) vimentin Ovary: AE1/AE3 AFP ARID1A calretinin CK7 …
Pathology Outlines - IHC panels
Pancytokeratins and CK7 should not be used in this differential diagnosis, as both metastatic carcinoma and mesothelioma can express them (Arch Pathol Lab Med 2013;137:647, Mod …
Pathology Outlines - Oncocytoma
CK7 positive (however, sometimes patchy in eosinophilic chromophobe) S100A1 usually negative Hybrid oncocytic / chromophobe tumors (HOCT) (Mod Pathol 2019;32:1698): Term usually …
Pathology Outlines - Cytokeratins (CK) - general
4 天之前 · Secondary CKs (e.g., CK19, CK7 and CK20) expressed alongside CK8 / 18 in most simple and complex epithelia (including urothelium, mesothelium and nonkeratinizing …