CHEK2 (Checkpoint kinase 2) is a tumor suppressor gene that encodes the protein CHK2, a serine-threonine kinase. CHK2 is involved in DNA repair, cell cycle arrest or apoptosis in …

2019年8月27日 · CHEK2 is a tumor-suppressor gene that protects cells from becoming cancerous. People who inherit mutations in the gene are at increased for certain types of …

2023年7月17日 · A CHEK2 gene mutation increases your risk for certain types of cancers. Your cancer risk may be different depending on the specific CHEK2 mutation you have. Most …

2023年12月19日 · CHEK2 是 “检测点激酶2（checkpoint kinase2）” 基因的缩写。 该基因为血细胞生产CHK2蛋白质提供指令，当细胞里的DNA损毁或DNA链断裂时，CHK2被激活。 CHK2 …

2025年1月18日 · Having the CHEK2 mutation means that your DNA contains a change in the CHEK2 gene, which plays a role in DNA repair and tumor suppression. This mutation …

2025年3月30日 · CHEK2 (Checkpoint Kinase 2) is a Protein Coding gene. Diseases associated with CHEK2 include Tumor Predisposition Syndrome 4 and Prostate Cancer. Among its …

检查点激酶 2： 为了响应 DNA 损伤和复制阻滞，细胞周期进程通过关键细胞周期调节剂的控制而停止。该基因编码的蛋白质是细胞周期检查点调节剂和推定的肿瘤抑制因子。它包含叉头相关 …

2025年3月14日 · An inherited CHEK2 mutation may affect your options for cancer prevention, detection and treatment. FORCE is here to guide you.

2023年12月11日 · Checkpoint kinase 2 (CHEK2) plays a crucial role in responding to DNA damage and is linked to diverse cancer types. However, its significance in the...

2021年10月4日 · CHEK2 serves the body as a tumor suppressor, but when it's mutated, it can be linked to numerous cancers. It is considered a more moderate-risk gene mutation. Today, …