2025年3月30日 · CDH2 (Cadherin 2) is a Protein Coding gene. Diseases associated with CDH2 include Agenesis Of Corpus Callosum, Cardiac, Ocular, And Genital Syndrome and Attention Deficit-Hyperactivity Disorder 8. Among its related pathways are Cell junction organization and Blood-Brain Barrier: Anatomy.

Cadherin-2 is a transmembrane protein expressed in multiple tissues and functions to mediate cell–cell adhesion. In cardiac muscle, Cadherin-2 is an integral component in adherens junctions residing at intercalated discs, which function to mechanically and electrically couple adjacent cardiomyocytes.

N-cadherin也叫做神经钙黏蛋白（Neural-cadherin/Cadherin-2），是一种钙依赖的单链跨膜糖蛋白，介导细胞的同型和异型粘附。 N-cadherin由疏水跨膜区、细胞外区和高度保守的c端细胞内 …

Yeruva等人以CDH2（N-Cadherin）重组蛋白（购自义翘神州，货号：11039-H03H）进行免疫染色解离、WB免疫印迹等分析，结果发现 致心律失常性心肌病 （AC）患者自身抗体对CDH2和DSG2具有催化活性，减少粘附分子间的相互作用。

该基因编码经典的钙粘蛋白和钙粘蛋白超家族的成员。 可变剪接导致多个转录变体，其中至少一个编码前原蛋白的变体经过蛋白水解处理以产生钙依赖性细胞粘附分子和糖蛋白。 这种蛋白质在左右不对称的建立、神经系统的发育以及软骨和骨骼的形成中发挥作用。 [RefSeq 提供，2015 年 11 月] This gene encodes a classical cadherin and member of the cadherin superfamily.

CDH2 belongs to the classic cadherin family of Ca2+-dependent cell adhesion molecules with a meticulously described dual role in cell adhesion and β-catenin signaling. During CNS development, CDH2 is involved in a wide range of processes including ...

2015年9月30日 · Thus, Cdh2 contributes to the establishment and maintenance of FGF signaling-dependent self-renewal in mEpiSCs through stabilization of FGFR1.

2025年1月4日 · FITC-labeled Tat 47-59 peptide downregulates gene expression of cadherin 2, type 1, N-cadherin (neuronal) (CDH2) in U-937 macrophages: PubMed

We summarize the existing knowledge regarding the role of CDH2 and CDH11 during development and differentiation in vivo and in vitro. We also discuss engineering strategies to control stem cell fate decisions by fine-tuning the extent of cell-cell adhesion through surface chemistry and microtopology.

2022年9月23日 · CDH2 belongs to the classic cadherin family of Ca 2+-dependent cell adhesion molecules with a meticulously described dual role in cell adhesion and β-catenin signaling. During CNS development, CDH2 is involved in a wide range of processes including maintenance of neuroepithelial integrity, neural tube closure (neurulation), confinement of ...