A CD8+ NK cell transcriptomic signature associated with clinical ...
2021年1月27日 · We identify surrogate markers of the NK8 + signature in peripheral blood leucocytes and validate their association with clinical outcome in an independent cohort, …
Advanced Science：田志刚院士团队揭示NK细胞辅助功能的调控机 …
NK细胞TIPE2通过抑制转录因子T-bet和Eomes及其下游的效应分子的表达，间接限制了抗肿瘤CD8+ T细胞的功能，提示TIPE2是NK细胞辅助功能的卡控点分子。 中国科学技术大学田志刚 …
NK cell development, homeostasis and function: parallels with CD8 …
2011年8月26日 · In this Review, we highlight the many stages that an NK cell progresses through during its remarkable lifetime, discussing similarities and differences with its close relative, the …
Induced CD8α identifies human NK cells with enhanced ... - PubMed
2024年5月28日 · The surface receptor CD8α is present on 20%-80% of human (but not mouse) NK cells, yet its function on NK cells remains poorly understood. CD8α expression on donor …
Adv Sci：田志刚院士团队揭示NK细胞辅助功能的调控机制，协同 …
2023年2月27日 · 科研团队的研究表明NK细胞TIPE2通过抑制转录因子T-bet和Eomes及其下游的效应分子的表达，间接限制了抗肿瘤CD8+T细胞的功能，提示 TIPE2是NK细胞辅助功能的免疫 …
CD8+ T Cells and NK Cells: Parallel and Complementary Soldiers …
In this review, we will compare and contrast two cytotoxic cells, CD8 + T cells in adaptive immunity and NK cells in innate immunity, and further discuss recent advances in cancer …
Allogeneic NK cells with a bispecific innate cell engager in
1 天前 · (b) Plots showing the percentage (%) of B cells, CD8 + T cells, CD4 + T cells, γδ T cells and NK cells within the gated CD45 + PBMC population at different timepoints during the …
NK-like CD8 T cell: one potential evolutionary continuum between ...
2024年7月12日 · This review aimed to deduce the possible differentiation model of NK-like CD8 T cells, summarize the functions of major NK-cell receptors expressed on these cells, and …
CD8αα Expression on NK cells is Associated with Different K562 …
CD8αα expression on the NK cells is associated with the effective cytotoxicity against K562 but obstructs a response to MOLT4. CD8αα on NK cells might participate in HLA recognition or …
New insights on anti-tumor immunity of CD8+ T cells: cancer stem …
2025年3月17日 · Notably, CD8+ T cells are one of the primary tumor-infiltrating immune cells that provide anti-tumor response. Tumor cells and tumor stem cells will resist or evade destruction …