CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. Phosphate-buffered solution, pH …

cd8+ t细胞是一种效应性t细胞，主要负责清除感染的细胞和肿瘤细胞。 当内源性抗原被细胞自身处理后，会形成MHC-I-抗原复合物，然后与CD8+ T细胞相互作用。

CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation.

CD8 plays important roles in T cell activation and selection. The extracellular IgSF domain of CD8α binds to a non-polymorphic determinant on HLA class I molecules (α3 domain) and enables CD8 to function as a co-receptor with MHC class I-restricted TCR …

Anti-human CD8, clone UCHT-4, is a monoclonal antibody designed to be used as a direct immunofluorescence reagent in order to identify cells that express the CD8 antigen by flow cytometry. Allophycocyanin (APC), is part of the BD family of phycobiliprotein dyes.

Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine production, motility and cytotoxic T lymphocyte (CTL) activation. Once activated, CTLs play a crucial role in the clearance of pathogens and tumor cells.

Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine production, motility and cytotoxic T lymphocyte (CTL) activation. Once activated, CTLs play a crucial role in the clearance of pathogens and tumor cells.

CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. Phosphate-buffered solution, pH …

apc通过mhc-i向cd8+t细胞呈递抗原肽 所有有核的细胞都有MHC-I，这些细胞均可以通过 蛋白酶体 降解胞内的蛋白质，部分蛋白质经过加工交给MHC-I; 类似一个工厂抽检环节；如果此时细胞被病毒感染，病毒在细胞内产生病毒来源的蛋白质，那么这套抽检系统就可以呈递 ...

Allophycocyanin (APC) is a stable and highly soluble phycobiliprotein that provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thus providing exceptional quantum yields and molar extinction coefficients.