In this study, we demonstrate that CD49b subdivides the most primitive HSC compartment into functionally distinct subtypes: CD49b − HSCs are highly enriched for myeloid-biased and the …

Jul 12, 2022 · In this study, we demonstrate that CD49b subdivides the most primitive HSC compartment into functionally distinct subtypes: CD49b - HSCs are highly enriched for myeloid …

Cell membrane receptors used to differentiate leukocyte subpopulations. Examples: CD49b, CD34, etc. A family of cytokines that work through G protein–coupled receptors to induce …

CD49b is expressed on NK cells and a small population of T cells (CD4 + CD3 + TCRα/β +). CD49b is less mouse strain–specific than other NK cell markers (e.g. NK1.1) and is expressed …

CD49b is expressed on a fraction of effector T cells in the context of arthritis, influenza or LCMV infection, and in tumors, whereas CD49a expression is largely confined to effector cells …

Invitrogen Anti-CD49b (Integrin alpha 2) Monoclonal (DX5), eBioscience™, Catalog # 11-5971-82. Tested in Flow Cytometry (Flow) applications. This antibody reacts with Mouse samples. …

Apr 28, 2013 · By gene expression profiling of human Tr1 cell clones, we identified the surface markers CD49b and lymphocyte activation gene 3 (LAG-3) as being stably and selectively …

cd49b：由于还会表达在胸腺上皮细胞、b细胞、单核细胞等中，在用于nk鉴定时，更推荐抗原克隆位点为dx5的抗体，特异性会更强，基本所有小鼠品系都表达，但在nod中不表达。 小鼠nk细 …

Jul 12, 2022 · Our studies demonstrate that CD49b can distinguish between functionally and epigenetically distinct multipotent HSCs with myeloid and lymphoid bias in the primitive HSC …

Oct 1, 2008 · We demonstrate using both in vitro and in vivo assays that the CD49b + CD8 T cell population is a far more potent antitumor effector cell population than nonfractionated CD8 or …