2022年7月12日 · In this study, we demonstrate that CD49b subdivides the most primitive HSC compartment into functionally distinct subtypes: CD49b - HSCs are highly enriched for myeloid …

In this study, we demonstrate that CD49b subdivides the most primitive HSC compartment into functionally distinct subtypes: CD49b − HSCs are highly enriched for myeloid-biased and the …

Cell membrane receptors used to differentiate leukocyte subpopulations. Examples: CD49b, CD34, etc. A family of cytokines that work through G protein–coupled receptors to induce …

CD49b is expressed on NK cells and a small population of T cells (CD4 + CD3 + TCRα/β +). CD49b is less mouse strain–specific than other NK cell markers (e.g. NK1.1) and is expressed …

CD49b is expressed on a fraction of effector T cells in the context of arthritis, influenza or LCMV infection, and in tumors, whereas CD49a expression is largely confined to effector cells …

2013年4月28日 · By gene expression profiling of human Tr1 cell clones, we identified the surface markers CD49b and lymphocyte activation gene 3 (LAG-3) as being stably and selectively …

The suppressive function of T-regulatory cells (Tregs) can have a detrimental effect on immune responses against tumor cells. Within the Treg cells subset, a new non-classical population …

This data suggests that CD49b may be a marker of the failure of the immune response and antiviral therapy during HCV recurrence. The assessment of CD49b could help to select …

2022年7月12日 · Our studies demonstrate that CD49b can distinguish between functionally and epigenetically distinct multipotent HSCs with myeloid and lymphoid bias in the primitive HSC …

The results showed that the expression of CD49b (a predominant marker of Tr1) before the introduction of antiviral therapy was significantly associated with SVR. Responders displayed …