CD44是一种复杂的跨膜粘附糖蛋白，表达于人的多种细胞，包括胚胎干细胞、分化细胞和癌细胞。 转录过程中不同的选择性剪接，产生CD44的两种亚型，包括标准亚型 (CD44s)和CD44变 …

2019年1月10日 · CD44v6 assists colorectal cancer stem cells in colonization, invasion, and metastasis. CD44v6 improves CRC resistance to anti-cancer therapy by stabilizing the...

Here we will give an overview of immunohistochemically determined CD44v6 expression in human malignancies (primary epithelial and nonepithelial tumours as well as metastases) and …

2023年11月24日 · Molecular radiotherapy combines the advantages of systemic administration of highly specific antibodies or peptides and the localized potency of ionizing radiation. A …

2014年3月6日 · Here, we show that all colorectal cancer stem cells (CR-CSCs) express CD44v6, which is required for their migration and generation of metastatic tumors. CD44v6 expression …

外显子 6 (cd44v6) 的表达为标准 cd44 带来了额外的特性，如与骨桥蛋白的结合以及与不同的酪氨酸激酶受体 (rtk)（如 vegf 受体 ii 型和 c-met）的合作。有趣的是，cd44v6 是 aml 和 mm 中表 …

CIC are characterized by sets of markers, mostly membrane anchored adhesion molecules, CD44v6 being the most frequently recovered marker. Knockdown and knockout models …

2014年3月6日 · Here, we show that all colorectal cancer stem cells (CR-CSCs) express CD44v6, which is required for their migration and generation of metastatic tumors. CD44v6 expression …

2018年5月10日 · CD44v6 can recruite ezrin/radixin/moesin (ERM) proteins that promote cytosketal changes and that may interact with VEGFR contributing angiogenesis, cancer cell …

CD44v6 is an isoform of the hyaluronic receptor CD44 that is almost exclusively expressed at high levels on solid cancers and has been associated with tumorigenesis, tumor cell invasion and …