
The biology and role of CD44 in cancer progression: therapeutic ...
Here, we review current data on the structural and functional properties of CD44, the known roles for CD44 in tumorigencity, the regulation of CD44 expression, and the potential for targeting …
CD44 Gene - GeneCards | CD44 Protein | CD44 Antibody
Mar 28, 2025 · CD44 (CD44 Molecule (IN Blood Group)) is a Protein Coding gene. Diseases associated with CD44 include Hematologic Cancer and Congenital Dyserythropoietic Anemia. …
CD44: From adhesion molecules to signalling regulators
Jan 1, 2003 · CD44 and its associated partner proteins monitor changes in the extracellular matrix that influence cell growth, survival and differentiation.
Differences in CD44 Surface Expression Levels and Function ...
CD44 is a prominent activation marker which distinguishes memory and effector T cells from their naïve counterparts. It also plays a role in early T cell signaling events as it is bound to the …
CD44 - an overview | ScienceDirect Topics
CD44 is a widely distributed transmembrane cell adhesion molecule that is probably the most well-characterized receptor for HA (Aruffo et al., 1990). CD44–HA interaction is involved in …
CD44: A Multifunctional Mediator of Cancer Progression - PMC
CD44, a non-kinase cell surface transmembrane glycoprotein, has been widely implicated as a cancer stem cell (CSC) marker in several cancers. Cells overexpressing CD44 possess …
CD44: A Multifunctional Cell Surface Adhesion Receptor Is a …
Mar 6, 2017 · CD44 is a cell surface adhesion receptor that is highly expressed in many cancers and regulates metastasis via recruitment of CD44 to the cell surface. Its interaction with …
CD44 regulates epigenetic plasticity by mediating iron endocytosis - Nature
Aug 3, 2020 · CD44 is a cell-surface adhesion receptor associated with many biological processes that rely on cellular plasticity. Now, CD44 has been shown to mediate endocytosis …
CD44 as a tumor biomarker and therapeutic target
Dec 10, 2020 · In this review, we focus on current data relevant to CD44, and outline CD44 structure, the regulation of CD44, functional properties of CD44 in carcinogenesis and cancer …
CD44 on cancer stem cell is a potential immunological and …
1 day ago · CD44, a widely recognized cancer stem cell marker, displayed a vital participation in the cancer immune invasion and may related with the response to the immunotherapy. …
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