2019年9月9日 · The CD4 + CD57 + T cell population exhibits higher frequencies of IFN-γ- and TNF-α-producing cells than the CD4 + CD57 − T cell population. PBMCs were stimulated with …

The CD57 antigen (alternatively HNK-1, LEU-7, or L2) is routinely used to identify terminally differentiated 'senescent' cells with reduced proliferative capacity and altered functional …

2024年5月16日 · In this study, we found that in SLE patients: (1) the frequency of CD4 + CD57 + senescent T cells was significantly elevated and positively correlated with disease activity; (2) …

2005年12月15日 · HIV-1-specific CD4+ T cells producing only IFN-gamma had the highest expression of CD57, whereas few cells producing IL-2 alone expressed CD57. These findings …

CD57 has been shown to be present on both CD4 and CD8 T-cells in the late stages of differentiation . Late-differentiated T cells are generally thought to exhibit a phenotype …

In this study, we found that in SLE patients: (1) the frequency of CD4 CD57 senescent T cells was significantly elevated and positively correlated with disease activity; (2) the expression levels …

1992年4月1日 · Together, the study of the CD7 and CD57 expression on CD4 + lymphocytes from HIV-infected patients gave us two important results: (1) the levels of CD4 + CD7-CD57 + …

2019年3月13日 · The loss of the co-stimulatory molecule CD28 and the gain of CD57 expression are prominent markers of the aging immune system in human CD4 + or CD8 + T cells 12, 13. …

In summary, we have shown that CD57 + memory T cells in the CD4 + and CD8 + lineages self-renew in vivo, enabling the long-term maintenance of functionally replete immunological …

2021年7月26日 · High gene expression of CD4, KLRG-1, and B3GAT1 (CD57), which correlates with increased overall survival for BC patients, underscores the usefulness of the evaluation of …