2021年12月8日 · Using mouse models, we show that inducible CD36 is required for free fatty acid uptake by HSCs during acute infection, allowing the metabolic transition from glycolysis …

2020年9月21日 · Here, we show that FAs trigger caveolae-dependent CD36 internalization, which in turn delivers FAs into adipocytes. During the process, binding of FAs to CD36 activates its …

2021年9月24日 · There are emerging studies into the mechanisms of free fatty acid (FFA) import and metabolism in breast cancer microenvironment, however, several aspects of the process …

2021年12月8日 · Using mouse models, we show that inducible CD36 is required for free fatty acid uptake by HSCs during acute infection, allowing the metabolic transition from glycolysis …

2014年10月13日 · In this model, humans with reduced tissue CD36 content will have lesser FFA uptake when FFA concentrations fall below overnight postabsorptive levels, whereas those …

2017年12月8日 · In adipocytes CD36 binds and internalizes lipoproteins and long-chain FFA. In line with other reports, a recent study showed that in CD36-null mice adipocytes' lipid uptake is …

2022年8月6日 · In obesity, chronic membrane-localization of CD36 free fatty acid (FFA) translocase, but not other FFA transporters, enhances FFA uptake and intracellular lipid …

2011年2月11日 · We report the first measurements of the intracellular unbound FFA concentrations (FFA (i)) in cardiomyocytes. The fluorescent indicator of FFA, ADIFAB …

2016年10月1日 · CD36 is a multifunctional immuno-metabolic receptor with many ligands. One of its physiological functions in the heart is the high-affinity uptake of long-chain fatty acids (FAs) …

Animal models have demonstrated that CD36 facilitates cell membrane free fatty acid (FFA) transport, but its role in human metabolism is not well understood. We measured heart, liver, …