Mature blood vessels consist of endothelial cells and pericytes/smooth muscle cells, stabilizing vascular structures and controlling their permeability. A mature blood vessel would be presented as a vessel of CD31 (+) and αSMA (+); an immature blood vessel would be presented as a vessel of CD31 (+) and αSMA (–).

如题，我做了血管新生双染，cd31红光，sma绿光，并标记了核。请问下大侠们如何进行下一步分析？

Download scientific diagram | Angiogenesis evaluated by α-SMA and CD31 staining. (A): Representative images of α-SMA and CD31 staining in peri-infarcted region at the endpoint in each group.

心肌梗死 （myocardial infarction，MI）后炎症消退和启动心脏修复需要及时激活修复信号，而 组蛋白乳酸化 （histone lactylation）在 巨噬细胞 中通过转录调节发挥自我平衡的基因表达特征。 然而，组蛋白乳酸化在 MI后（post-MI）修复反应 中的作用尚不明确。 因此，组蛋白乳酸化在MI后早期和远期如何诱导 单核细胞 中的基因表达非常值得探索，这有助于 治疗MI。

2023年10月1日 · The objective of this study was to evaluate the expression of CD31-positive blood vessels and α-smooth muscle action (α-SMA)-positive myofibroblasts in granulation tissue in order to evaluate their value as markers for porcine wound age estimation in a veterinary forensic context.

Immunohistochemistry is an integral component in the proper analysis of soft tissue tumours, and a simple panel of six markers is useful in practical triage: CD34, desmin, epithelial membrane antigen (EMA), keratin cocktail AE1/AE3, S100 protein and alpha smooth muscle actin (SMA).

2018年5月15日 · 在免疫组化中，CD31 是主要用于证明内皮细胞组织的存在，用于评估肿瘤血管生成，这可能意味着一个快速增长的肿瘤的程度。 恶性血管内皮细胞通常也保留抗原，所以，CD31 免疫组织化学方法还可以用于证明血管瘤和 血管肉瘤。 它还可证明在小淋巴细胞和淋巴细胞性淋巴瘤，但CD31并非他们特异的标志分子 。 6. Ki67染色. Ki67是一种增殖细胞相关的核抗原，其功能与有丝分裂密切相关,在细胞增殖中是不可缺少 ,但其确切机制尚不清楚，Ki67作为标 …

近年来，分化簇 31 (cd31)、鬼笔环肽和α平滑肌肌动蛋白 (α-sma) 被广泛应用于标记脑血管。尽管cd31主要用作确定脑毛细血管的内皮标记物，但其标记效率似乎与多克隆抗体或单克隆抗体以及血管状况密切相关。

Results: Adenocarcinomas showed significantly higher staining scores of both VEGF and αSMA than squamous cell carcinomas did. In 42 cases of high CD31 score, five-year survival rate (87%) of patients with lung cancer showing mature tumor vessels was significantly better than that (69%) of patients with immature tumor vessels.

2022年12月24日 · Cluster of differentiation 31 (CD31), phalloidin and alpha smooth muscle actin (α-SMA) have been widely applied to label the cerebral blood vessels in the past years.