Learn how to activate T cells with functional antibodies CD3 and CD28 with this detailed protocol.

Dynabeads Human T-Activator CD3/CD28 beads are 4.5-μm superparamagnetic beads covalently coupled with an optimized combination of anti-human CD3 and anti-human CD28 …

CD28 (Cluster of Differentiation 28) is a protein expressed on T cells that provides essential co-stimulatory signals required for T cell activation and survival. When T cells are stimulated …

2003年4月1日 · A more physiologically relevant approach uses beads coated with anti-CD3 and anti-CD28 to stimulate T cells in a manner that partially mimics stimulation by antigen …

2003年11月1日 · CD28 costimulation plays an important role during T cell activation to promote T cell survival, augment production of cytokines, and overcome T cell anergy. 1,2 The use of …

We engineered two recombinant cross-interacting Bs-Abs (CriBs-Abs) by incorporating a peptide tag and its cognate single-chain variable fragment (scFv), respectively, into a pair of (tumor × …

In this mini-review, we provide an up-to-date overview of our understanding of the signaling mechanisms that underlie CD28 function and its potential application to the modulation of …

2018年10月15日 · Here we compared the sensitivity of non-stimulated (non-proliferating) vs. CD3/CD28-stimulated (proliferating) PBLC to IR. PBLCs were highly sensitive to IR and, …

The bispecific antibody (bsAb) CD3-CD28 is designed to activate and expand enriched T cell populations or T cells from peripheral blood mononuclear cells (PBMCs). Its efficacy in …

The CD3/CD28 Streptamer approach is based on our Strep-tag technology and facilitates T cell activation and expansion. Low affinity, Fab fragments fused to a Twin-Strep-tag (Fab-Streps) …