CD3 is an essential T cell co-receptorand defines T cell lineage. CD3is therefore an ideal T cell marker. This mini-review explains the structure of CD3, the genes involved in its expression, …

CD3-targeted immunotherapy has emerged as a promising strategy in cancer treatment. The goal is to enhance T-cell activation against tumor cells by focusing on the CD3 marker, which plays …

Anti-CD3 antibodies act as potent immunosuppressive agents by modulating the CD3/T-cell receptor (TCR) complex. They have been used in patients to prevent short term allograft …

Absolute CD3 cells, also known as CD3+ cells, refer to a subset of T-lymphocytes that express the CD3 marker on their surface. CD3 is a protein complex and T cell co-receptor involved in …

CD3 is a protein that is normally made by two types of specialized immune cells, T cells and NK cells. Most lymphomas that start from T and NK cells, including peripheral T cell lymphoma, …

In this review, we will focus on those strategies that directly target the CD3/TCR complex in situ—namely, CD3 specific antibodies, their variants, and CD3 aptamers (Table 1).

2024年6月7日 · Explore the essential role of CD3 in T cell activation and immune response. Learn about its structure, function, and clinical significance in immunotherapy and diagnostics.

The biomarker CD3+/CD4-/CD8- identifies a unique subset of T lymphocytes that express the CD3 surface protein but lack both CD4 and CD8 co-receptors. These cells are often referred …

Substances Antibodies, Monoclonal Biomarkers, Tumor CD3 Complex Receptors, Antigen, T-Cell

2025年3月29日 · Objective To evaluate the efficacy of anti-CD3 monoclonal antibody (mAb) in patients with type 1 diabetes (T1D) and identify the influencing factors. Methods Randomized …