
CD2AP - Wikipedia
CD2-associated protein is a protein that in humans is encoded by the CD2AP gene. [5][6] This gene encodes a scaffolding molecule that regulates the actin cytoskeleton.
CD2AP Gene - GeneCards | CD2AP Protein | CD2AP Antibody
2025年3月28日 · CD2AP (CD2 Associated Protein) is a Protein Coding gene. Diseases associated with CD2AP include Focal Segmental Glomerulosclerosis 3 and Hereditary Steroid-Resistant Nephrotic Syndrome. Among its related pathways are Cell junction organization and Cytoskeletal Signaling.
CD2AP - 维基百科,自由的百科全书
CD2相關蛋白質 (CD2-associated protein)是在人類中由CD2AP 基因 所編碼的 蛋白質。 [1][2] 該基因編碼一種調節肌動蛋白細胞骨架的"支架分子" (在神經元通路中的廣大連結區域聚積的蛋白分子)。
CD2AP与阿尔茨海默病 - 知乎专栏
研究发现 CD2AP 通过调控淀粉样前体蛋白 (APP) 的转运和降解过程影响 Aβ 代谢。 实验表明,CD2AP 缺失会导致 Aβ 生成增加和清除减少,加速斑块形成。 " CD2AP 在淀粉样蛋白调控中具有双重角色,"张教授解释," 它既能限制 Aβ 的过度生成,又能辅助清除毒性淀粉样聚集体。 任何一方面的功能失调都可能打破平衡,引发神经退行性病变。 突触完整性:CD2AP的双刃剑效应. 突触丢失是 AD 认知能力下降的重要预测指标,而 CD2AP 对维持突触结构和功能至关重要。 但 …
CD2AP - 维基百科,自由的百科全书 - zh.wikipedia.org
CD2相关蛋白质 (CD2-associated protein)是在人类中由CD2AP 基因 所编码的 蛋白质。 [1][2] 该基因编码一种调节肌动蛋白细胞骨架的"支架分子" (在神经元通路中的广大连结区域聚积的蛋白分子)。
CD2AP在阿尔茨海默病发病进程中作用的研究进展
CD2AP(CD2-associated protein)作为一种适配器蛋白,与细胞内蛋白转运以及细胞骨架重塑密切相关。 CD2AP被发现是AD的一个风险因子。 目前的研究显示CD2AP能够影响Aβ的生成和沉积以及参与介导Tau蛋白的神经毒性。 此外,CD2AP对血脑屏障的完整性和突触囊泡的转运也有 ...
The role of CD2AP in the Pathogenesis of Alzheimer's Disease
Although the association between CD2AP and higher risk of AD has been well addressed, the mechanisms of CD2AP implicated in AD pathogenesis still unclear. More and more evidence reveals that CD2AP loss of function results to enhanced Aβ metabolism, Tau-induced neurotoxicity, synapse dysfunction and abnormal neurite structure.
23607 - Gene ResultCD2AP CD2 associated protein [ (human)]
2025年1月4日 · CD2AP is indicated as a protein up-regulated by HCV infection, which, in turn, stimulates HCV propagation and steatosis by disrupting insulin signaling; targeting CD2AP may offer an opportunity for alleviating HCV infection and its associated liver pathology
CD2AP_百度百科
CD2AP (CD2-associated protein)是在人类中由CD2AP 基因 所编码的 蛋白质。 该基因编码一种调节肌动蛋白细胞骨架的"支架分子" (在神经元通路中的广大连结区域聚积的蛋白分子)。 该蛋白 …
CD2AP CD2 associated protein [Homo sapiens (human)] - Gene
2025年1月4日 · The upregulation of CD2-associated protein (CD2AP) could attenuate gastric cancer (GC) metastasis, suggesting CD2AP as a biomarker for the prognosis and treatment of patients with GC.