Description: The CD28.2 monoclonal antibody reacts with the human CD28 molecule, a 44 kDa homodimer expressed by thymocytes, mature T cells and plasma cells. CD28 is a ligand for CD80 (B7-1) and CD86 (B7-2) and is a potent co-stimulator of T cells.

Antibodies that detect CD28 can be used in several scientific applications, including Flow Cytometry, Western Blot, ELISA, Immunohistochemistry and Functional Assay. These …

Description: The CD28.2 monoclonal antibody reacts with the human CD28 molecule, a 44 kDa homodimer expressed by thymocytes, mature T cells and plasma cells. CD28 is a ligand for CD80 (B7-1) and CD86 (B7-2) and is a potent co-stimulator of T cells.

t淋巴细胞表面的协同刺激分子cd28与其配体b7的相互作用是为t淋巴细胞活化提供第二信号的主要途径之一。如果可以在体外利用cd3抗体刺激提供第一信号的同时，用cd28抗体协同刺激提供第二信号，就可以使t淋巴细胞充分活化。

The CD28 antibody recognizes the human CD28 antigen, a type I transmembrane protein, which is highly expressed on CD3+ thymocytes, most peripheral thymocytes and plasma cells. Binding of CD28 to its ligands CD80 or CD86 costimulates T cell effector function and T cell–dependent antibody production in vitro and in vivo.

The 37.51 monoclonal antibody reacts with mouse CD28, a 45 kDa costimulatory receptor and a member of the Ig superfamily. CD28 is expressed by thymocytes, most peripheral T cells, and NK cells. CD28 is a receptor for CD80 (B7-1) and CD86 (B7-2).

CD28mAb 与 CD28 结合可提供细胞表面活化的第二信号，从而促进 T 细胞增殖。 研究表明， CD28 mAb也能促进CIK 细胞增殖，对 CIK 细胞分泌 IFN-γ、 TNF-α 和 IL-2 有促进作用，对CIK 细胞的杀伤活性有增强作用。

CD28 (D2Z4E) Rabbit mAb recognizes endogenous levels of total CD28 protein and is predicted to react with multiple CD28 isoforms that are produced through alternative splicing. This antibody cross-reacts with 16 kDa and 100 kDa proteins of unknown origin in some mouse cells.

2025年3月31日 · Human CD28 Activating (CD28.2) Mouse mAb (Low Endotoxin, Azide-free) recognizes endogenous levels of CD28 protein. Monoclonal antibody is produced using cells transfected with human CD28 and purified via affinity chromatography. CD28 is a transmembrane glycoprotein expressed by T cells as well as some other hematopoietic cells (1, 2).