Cluster of Differentiation 276 (CD276) or B7 Homolog 3 (B7-H3) is a human protein encoded by the CD276 gene. [5] B7-H3 is a 316 amino acid-long type I transmembrane protein, existing in …

Mar 30, 2025 · CD276 (CD276 Molecule) is a Protein Coding gene. Diseases associated with CD276 include Long Qt Syndrome and Glioma Susceptibility 1 . Among its related pathways …

Mar 20, 2022 · B7-H3 (also known as CD276) is a newly found molecule of B7 family, which may be a promising target for cancer treatment. B7-H3 protein was demonstrated to be expressed …

B7-H3 (also known as CD276), a member of the B7 family of immune checkpoint proteins, is highly expressed in cancer cells and activated tumor-infiltrating immune cells, and helps …

Mar 26, 2021 · CD276 plays an essential role in cell proliferation, invasion, and migration in malignancies. Results from most recent studies indicate CD276 could be a promising …

Jul 21, 2021 · Our data show a role for tumor-expressed CD276 on the macrophage recruitment into the tumor spheroid, and also in regulation of the extracellular matrix modulator PAI-1.

Apr 1, 2024 · CD276 (B7-H3) is an immune checkpoint that belongs to the B7 immune co-stimulatory and co-inhibitory family. Protein level of CD276 is often elevated in tumor cells and …

Jul 15, 2016 · B7-H3 (CD276) is an important immune checkpoint member of the B7 and CD28 families. Induced on antigen-presenting cells, B7-H3 plays an important role in the inhibition of …

Jul 19, 2021 · B7 homolog 3 protein (B7-H3, also known as CD276), a newly identified immunoregulatory protein member of the B7 family, is an attractive and promising target for …

CD276/B7-H3 represents a promising target for cancer therapy based on widespread overexpression in both cancer cells and tumor-associated stroma.