CCR2 enhances CD25 expression by FoxP3 - Nature
2018年12月11日 · The bar graphs show the CD25 mean fluorescence index (MFI) of expression by FoxP3 + CD4 + (top) and FoxP3-CD4 + (bottom) T cells in 3 replicate wells with or without …
FOXP3 + regulatory T cell perturbation mediated by the IFNγ
2024年1月2日 · Further analysis indicated that IFITM3-deficient TI-Treg cells were more activated (higher expression of CD25) and proliferative (higher expression of Ki67) compared to TI …
Soluble CD25 imposes a low-zone IL-2 signaling ... - ScienceDirect
2023年2月1日 · Anti-CD25 mean fluorescence intensity (MFI) values are shown at designated sCD25 concentrations (Fig. 1 A-B). As expected, both mouse and human sCD25 recombinant …
Mouse IL-2/CD25 Fusion Protein Induces Regulatory T Cell …
2021年7月1日 · In this report, we show that the mIL-2/CD25 fusion protein is efficacious in inducing Treg expansion and inhibiting lupus nephritis in NZB × NZW F1 and MRL/lpr mice …
Functional defects in CD4+ CD25high FoxP3+ regulatory cells in
2016年11月30日 · Here, we investigated Treg function and found that Tregs in peripheral blood (PB) from patients with active AS had lower FoxP3 mean fluorescence intensity (MFI) than …
Double-negative T cells in combination with ursodeoxycholic acid ...
1 天前 · CD4⁺CD25⁺Foxp3⁺ Tregs regulate immune responses through the secretion of inhibitory cytokines such as IL-10 and TGFβ, whereas DNT primarily rely on perforin and granzyme B …
Assessing IL-2-Induced STAT5 Phosphorylation in Fixed, Permeabilized ...
2020年12月18日 · The relative abundance of intracellular pSTAT5 is most effectively visualized by determining the fold increase of pSTAT5 in IL-2-treated cells over medium-treated cells. To …
Distinct use of super-enhancer elements controls cell type–specific ...
2023年11月3日 · (A to C) Flow cytometry profiles for CD25 expression (MFI) gated on CD4 + FoxP3 + thymic and splenic cells from mice with upstream and intronic deletions in the Il2ra …
CCR2 enhances CD25 expression by FoxP3 - PubMed Central (PMC)
The MFI of CD25 expression is shown for CpG-stimulated WT and CCR2−/− FoxP3 + Tregs (top), and the fold changes in CD25 expression compared to that of unstimulated Tregs are also …
Soluble CD25 imposes a low-zone IL-2 signaling environment that …
Anti-CD25 mean fluorescence intensity (MFI) values are shown at designated sCD25 concentrations (Fig 1A–B). As expected, both mouse and human sCD25 recombinant proteins …