The interleukin-2 receptor alpha chain (also called Tac antigen, P55, and mainly CD25) is a protein involved in the assembly of the high-affinity interleukin-2 receptor, consisting of alpha …

2023年4月1日 · CD25 is the alpha-chain of the heterotrimer IL-2 receptor. CD25 is expressed on the surface of both immune and non-immune cells with different frequencies. For cancers, …

IL-2 binds to the IL-2 receptor, which has three forms, generated by different combinations of three different proteins, often referred to as "chains": α (alpha) (also called IL-2Rα, CD25, or …

CD25 (also known as IL-2Rα receptor or the α-subunit of the IL-2 receptor) is involved in the regulation of T cell function. More specifically, it is encoded by the CD25 region on …

CD25, expressed and secreted by such DC may capture IL-2 and thereby suppress T-cell proliferation, by this means providing an accessory mechanism of DC-mediated immune …

2023年3月22日 · Regulatory T (Treg) cells suppress NK cell activity through various mechanisms including deprivation of IL-2 via the IL-2 receptor alpha (CD25). Here, we investigate CD25 …

The gene expression for interleukin-2 receptor subunit alpha (CD25/IL2RA) is frequently altered in adults with acute myeloid leukemia (AML). Increasing evidence indicates that the elevated …

This observation suggests that CD25 could be modified in homologous IL-2/CD25 FPs to yield variants that form dimers of distinctive stability and activity. Our in vivo and in vitro studies …

CD25 + B cells display a complete IL-2 receptor and respond to IL-2. As CD25 represents one of three chains of the IL-2 receptor, we analysed the expression of the entire IL-2 receptor …

2021年4月16日 · The insight this question sparked came from considering CD25’s function. To date, Quezada had seen CD25 primarily as simply an antigen on Tregs, to which an antibody …