CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It has also been called T-cell surface antigen T11/Leu-5, LFA-2, [5] LFA-3 receptor, erythrocyte receptor and rosette receptor.

Mar 30, 2025 · CD2 (CD2 Molecule) is a Protein Coding gene. Diseases associated with CD2 include Mastocytosis, Cutaneous and Extracutaneous Mastocytoma. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway.

Jun 8, 2020 · Overall, CD2 is an attractive target for monoclonal antibodies intended for treatment of pathologies characterized by undesired T cell activation and offers an avenue to more selectively target memory T cells while favoring immune regulation.

绵羊红细胞受体（sheep red blood cell receptor，SRBCR ），即CD2，LFA-2。 可表达于所有外周血T细胞、95%以上人类胸腺细胞、大多数NK 细胞及部分恶变B细胞表面，但正常B细胞不表达。

CD2 （分化簇2，英語： cluster of differentiation 2）是一个 细胞黏附分子，是 T细胞 和 自然杀伤细胞 （NK细胞）共有的细胞表面标志物，也称为“T细胞表面抗原T11”（T-cell surface antigen T11）、LFA-2、LFA-3受体、“红细胞受体”（erythrocyte receptor）等 [5][6]。

Jul 8, 2024 · CD2是一种跨膜糖蛋白，属于免疫球蛋白超家族成员。 它广泛存在于T淋巴细胞表面，特别是在辅助性T细胞和某些亚群的细胞上表达较多。 CD2分子结构包含胞外区、胞内区和跨膜区，其中胞外区负责与其他细胞表面的分子结合，参与细胞间的相互作用。 CD2的功能. CD2的主要功能是参与细胞间的信号传导和黏附作用。 它通过与其它免疫细胞表面的分子结合，如整合素等，影响细胞间的识别和信号传导。 在T细胞的活化、增殖和分化过程中起到关键作用，有助于 …

CD2，即T细胞分化抗原2，别名Tp44、LFA-2、OKT11、T2等。 它是一种由CD2基因编码的细胞表面糖蛋白，属于免疫球蛋白超家族成员，主要表达在所有成熟T细胞和一些自然杀伤 (NK)细胞表面。

Jun 9, 2020 · The glycoprotein CD2 is a costimulatory receptor expressed mainly on T and NK cells that binds to LFA3, a cell surface protein expressed on e.g., antigen-presenting cells. CD2 has an important role in the formation and organization of the immunological synapse that is formed between T cells and anti …

Feb 17, 2024 · CD2蛋白是一种跨膜糖蛋白，是最早的T细胞标记物之一，广泛表达于人类T细胞、自然杀伤细胞（NK细胞）、部分B细胞和单核细胞等免疫细胞表面。

CD2 is a transmembrane molecule belonging to the immunoglobulin supergene family that plays a crucial role in T-cell activation, cytolysis, apoptosis, and cytokine production. It is expressed by thymic T-cells, peripheral T-cells, NK cells, and a subset of …