
CD1A - Wikipedia
CD1a (C luster of D ifferentiation 1a) is a human protein encoded by the CD1A gene. [3] This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin.
脂质抗原呈递分子CD1a - 知乎 - 知乎专栏
cd1a蛋白是一种跨膜蛋白,属于cd1家族,它在免疫系统中发挥重要作用。cd1家族包括cd1a、cd1b、cd1c和cd1d,它们与抗原呈递和t细胞免疫反应密切相关:与经典的主要组织相容性复合物(mhc)相比,cd1蛋白在抗原呈递…
CD1A Gene - GeneCards | CD1A Protein | CD1A Antibody
2025年3月30日 · CD1A (CD1a Molecule) is a Protein Coding gene. Diseases associated with CD1A include Histiocytosis and Langerhans Cell Histiocytosis. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation.
人 CD 抗原完全指南 - Abcam中文官网
cd1a-胸腺皮质细胞、朗格汉斯细胞、树突细胞和特定 t 细胞白血病。 将非肽抗原呈递给 nkt 细胞的 t 细胞受体,标记处于分化中短暂的胸腺皮质细胞阶段的 t 细胞。 cd1b-胸腺皮质细胞、朗格汉斯细胞和树突细胞。 将非肽抗原呈递给 nkt 细胞的 t 细胞受体。 cd1c-
cd1 - 百度百科
cd1(分化簇1)分为cd1a(r4),cd1b(r2),cd1c(r7),cd1d(r3)和cd1e(r2)五种。它们与mhcⅠ类分子的结构相似,可以提呈脂质或者糖脂质的抗原。另外,nkt细胞也只能接受由cd1d递呈的抗原。通常cd1分子在所有apc(抗原递呈细胞)和胸腺皮质细胞上都有表达。
CD1A - 维基百科,自由的百科全书
CD1a(Cluster of Differentiation 1a)是身上的一種人類蛋白质,由基因「CD1A」轉譯而成 [3] 。 該蛋白屬於CD1蛋白家族,為一種穿膜醣蛋白。CD1a與β2-微球蛋白共同構成的異源二聚體(heterodimers)稱為「CD1a複合體」(CD1a complex),在結構上類似MHC I分子。
Current Understanding of the Roles of CD1a-Restricted T Cells in …
CD1a is distinguished by the small volume of its antigen-binding groove and its stunted A′ pocket, its high and exclusive expression on Langerhans cells, and its localization in the early endosomal and recycling intracellular trafficking compartments. Its ligands …
CD1a 分子(CD1A)基因 | MCE - MCE-生物活性分子大师
cd1a 分子: 该基因编码跨膜糖蛋白 cd1 家族的成员,其在结构上与主要组织相容性复合体 (mhc) 蛋白相关,并与 β-2-微球蛋白形成异二聚体。 cd1 蛋白介导自身或微生物来源的主要脂质和糖脂抗原向 t 细胞的呈递。
CD1a promotes systemic manifestations of skin inflammation
2022年12月7日 · CD1a is a virtually monomorphic major histocompatibility complex (MHC) class I-like molecule, highly expressed by skin and mucosal Langerhans cells, and presents lipid antigens to T-cells. Here...
CD1a-mediated immunity from a molecular perspective
2023年6月1日 · Human CD1a is a non-polymorphic glycoprotein that presents lipid antigens to T cells. The most obvious role of CD1a is associated with its expression on Langerhans cells in epidermis, where it is involved in responses to pathogens.