
CD14 - Wikipedia
CD14 (cluster of differentiation 14) is a human protein made mostly by macrophages as part of the innate immune system. [5] [6] It helps to detect bacteria in the body by binding …
cd14 - 百度百科
CD14,即LPS(Lipopolysaccharide)受体,最初是一种存在于单核细胞、巨噬细胞等细胞表面的白细胞分化抗原,由TODD于1981年首次从人单核细胞表面发现。
CD14 - 维基百科,自由的百科全书
CD14(cluster of differentiation 14,分化簇14)是一种细胞表面蛋白质,主要在先天免疫系統的巨噬细胞上表达 [5] ,是最早发现的模式识别受体 [6] ,能参与识别脂多糖(LPS,一种病原相 …
CD14—细菌脂多糖的膜受体 - 知乎 - 知乎专栏
CD14(cluster of differentiation 14)原称MY23抗原,是一种表面抗原,属细胞表面糖蛋白家族成员之一。CD14基因编码的蛋白,优先表达于单核/巨噬细胞。CD14是革兰阴性菌内毒素脂多 …
Role of CD14 in human disease - PMC - PubMed Central (PMC)
The cell surface antigen CD14 is primarily understood to act as a co-receptor for toll-like receptors (TLRs) to activate innate immunity responses to pathogens and tissue injury in macrophages …
CD14 Gene - GeneCards | CD14 Protein | CD14 Antibody
2024年12月24日 · CD14 (CD14 Molecule) is a Protein Coding gene. Diseases associated with CD14 include Alagille Syndrome 1 and Croup. Among its related pathways are Toll Like …
CD14: Biology and role in the pathogenesis of disease
2019年8月1日 · Human monocyte differentiation antigen CD14 is a pattern recognition receptor (PRR) that enhances innate immune responses. CD14 was first identified as a marker of …
CD14的介绍:白细胞分化抗原与LPS受体的双重身份解析
2024年4月2日 · 根据CD14在体内的存在形式,分为存在于细胞表面的膜结合型CD14(membranebound CD14,mCD14)和血浆内的sCD14。 mCD14是一种分子量为5.3 …
CD14: Biology and role in the pathogenesis of disease - PubMed
In this review, we summarize advancements in the basic biology of the CD14 including its structure, binding ligands, signaling pathways, and its roles in the pathogenesis of …
Cell Reports丨CD14在细胞内LPS传感中的独立于TLR4的关键作用
CD14 是一种糖磷脂酰肌醇锚定的质膜蛋白,在 LPS 介导的 TLR4 激活中具有长期确定的作用;CD14 与 LPS 结合并将 LPS 转移到 TLR4-MD2 复合物,从而启动 myddosome 组装和信号 …