CD138：Syndecan-1在生命科学与临床诊断中的重要作用
2024年12月16日 · CD138，也被称为Syndecan-1，是一种重要的跨膜糖蛋白，在生命科学与临床诊断中扮演关键角色。 它作为浆细胞的标志性分子，在B细胞分化过程中呈现独特表达模式， …
Pathology Outlines - CD138
2024年6月13日 · CD138 is expressed in most triple negative breast cancers (TNBC). The increased expression of CD138 may contribute to the formation of a tumor supportive …
Syndecan 1 - Wikipedia
Syndecan-1 is a sponge for growth factors and chemokines, [7] with binding largely via heparan sulfate chains. The syndecans mediate cell binding, cell signaling, and cytoskeletal …
肿瘤免疫靶点 | CD138 - 知乎 - 知乎专栏
CD138 （syndecan-1、SDC1）是细胞外基质（ECM）的跨膜蛋白受体，其通过与乙酰肝素结合分子的相互作用介导细胞粘附，参与细胞增殖，迁移和细胞骨架的组织调节。CD138在恶性浆细 …
CD138：Syndecan 1在生命科学中的独特角色与应用
本文将深入探讨CD138的结构、表达模式、生物学功能以及在临床诊断和治疗中的应用。 CD138作为Syndecan家族的一员，具有四个跨膜糖蛋白结构，这一特点使其在细胞间信号传 …
Multiple myeloma cells expressing low levels of CD138 have an …
CD138 is a heparin sulphate proteoglycan that controls tumor cell survival, growth, adhesion and bone cell differentiation in MM (2).
CD138 - MyPathologyReport.ca
CD138 is a protein found on the surface of certain cells in the body. It plays a role in cell communication and adhesion, which means it helps cells stick together and send signals to …
CD138− plasma cell myeloma | Blood - American Society of …
2019年9月12日 · Recognizing the presence of CD138 − PCM combined with morphology and other plasma cell markers, such as CD38 and MUM1, will be helpful for a correct diagnosis. …
CD138 (syndecan-1), a plasma cell marker immunohistochemical …
Within the hematopoietic system, CD138 is an excellent marker of plasmacytic differentiation. Based on its broad staining profile, CD138 reactivity for neoplastic cells is not a definitive …
CD138 Plasma Cells: Significance, Regulation, Diagnostic Uses
2025年3月14日 · CD138, also known as syndecan-1, is a key surface marker of plasma cells with critical roles in immune function. It is involved in cell adhesion, signaling, and interactions …