18470-1-AP targets CD133 in WB, IHC, IF-P, ELISA applications and shows reactivity with human, mouse, rat samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. CD133, also known as PROM1 (prominin-1) or AC133, belongs to the prominin family.

Today CD133 is the most commonly used marker for isolation of cancer stem cell (CSC) population from different tumors, mainly from various gliomas and carcinomas. [16] Initial studies that showed ability of CD133-positive population to efficiently propagate tumor when injected into immune-compromised mice firstly were performed on brain tumors.

cd133作为一种公认的csc标志物，用于特异性鉴别不同种属csc的来源及疾病诊断，广泛应用于神经系统肿瘤、前列腺癌、结直肠癌等的干性特征筛选。

该研究团队开发了靶向 CD133 -GSC的嵌合抗原受体巨噬细胞（CAR-MΦ）免疫疗法，用于清除肿瘤切除后残留的CD133-GSCs。 本项研究证实，在 神经胶质瘤 GBM小鼠模型中，靶向CD133-GSCs，可发挥抗肿瘤免疫作用，抑制GBM术后的复发率，并减少抗肿瘤药物的毒副作用。 CD133又叫 PROM1，越来越多的实验证据支持PROM1可能是肿瘤（尤其是实体瘤）干细胞表面特异性表达的分子。 目前为止，已有临床研究将PROM1作为靶点或作为靶向性杀死肿瘤干细 …

CD133 (also called Prominin-1) is a pentaspan transmembrane glycoprotein widely used for stem and progenitor cell identification in several normal tissues and cancer stem-like cells of different types of cancer.

Monoclonal Antibody for studying CD133. Validated for IF, IHC, IHC, WB. Available in 2 sizes. Highly specific and rigorously validated in-house, CD133 (D2V8Q) XP® Rabbit Monoclonal Antibody (CST #64326) is ready to ship.

CD133 (also known as AC133 and prominin-1) is the most frequently used cell surface antigen to detect and isolate CSCs from various solid tumors , including brain, colon, pancreas, prostate, lung, and liver. There has recently been, however, some contrasting evidence of the accuracy associated with using CD133 as a marker for CSC detection and ...

2011年7月29日 · CD133 is known to be a cancer stem cell (CSC) marker. However, recent studies have revealed that CD133 is not restricted to CSC but to be expressed not only in human normal tissues but also in some cancers and could serve as a prognostic factor for the patients.

CD133, a pentaspan membrane glycoprotein, has been used as a stem cell biomarker for isolation of stem-like cells from a variety of normal and pathological tissues as well as cell lines since its discovery in 1999. Recent studies are focusing on the functionality of CD133.

2025年3月13日 · Notably, post-therapeutic PD-L1+ CD49f+ CD133+ numbers ≥ 5/ml in patients with vulvar cancer and ≥ 2/ml in patients with cervical cancer were associated with reduced recurrence-free survival on follow-up. Our study unravels individual therapy-induced changes in CTC phenotypic characteristics and occurrence in the patients’ blood and their ...