CCR2 is a host entry receptor for severe fever with ... - Science
2023年8月2日 · Here, by performing a genome-wide CRISPR-Cas9–based screen, we identified C-C motif chemokine receptor 2 (CCR2), a G protein–coupled receptor (GPCR), as a critical …
Induction of MCP1, CCR2, and iNOS Expression in THP-1 ... - Nature
2005年12月1日 · Unlike MCP-1 gene expression, CCR2 gene expression in the THP-1 macrophages was induced by serum obtained from both patients with and those without …
Association between CCR2 and CCL2 expression and NET ... - Nature
2023年7月27日 · NET induced in patients with AOSD enhanced the secretion of CCR2, higher CCR2 expression in monocytes, and the levels of interleukin (IL)-1β, IL-6, and IL-18 from THP …
The dual-function chemokine receptor CCR2 drives migration and …
2023年1月31日 · As a G protein–coupled receptor (GPCR), CCR2 promotes monocyte migration in response to the chemokine CCL2. As a scavenger receptor for CCL2, CCR2 sequesters …
Induction of MCP1, CCR2, and iNOS expression in THP-1
MCP-1 expression was significantly increased in the presence of serum from patients with coronary aneurysms. Expression of CCR2 and iNOS was significantly increased when THP-1 …
Kif4A mediate the accumulation and reeducation of THP-1
2017年5月22日 · In the present study, we show that, the interaction between THP-1derived macrophage and OSCC cell line Cal-27 may up-regulate the Kif4A expression in both of them. …
THP-1 cell migration in response to CCL2. (A) THP-1
We measured CCR2 expression in AML cell lines and primary AML cells by flow cyt... ... evaluate the role of CCL2 /CCR2 in AML biology, we first determined CCR2 expression in human AML …
The CCL2/CCR2 Axis Affects Transmigration and Proliferation but …
2017年1月3日 · Two cell lines expressed high levels of CCR2 (THP-1 and murine AML). RT-PCR and WB confirmed CCR2 production. CCL2 solid phase ELISA showed significantly lower …
Cilostazol reduces MCP-1-induced chemotaxis and adhesion of THP …
2011年7月29日 · This study aimed to investigate the modulating effect of cilostazol on the MCP-1-induced chemotaxis and adhesion of monocytes. The gene expression of CCR2, the major …
rhGM-CSF对单核细胞THP-1表达CCR2的影响 - 百度学术
有研究发现,ccr2基因敲除可抑制单核细胞在血栓中的聚集,mmp-2和mmp-9活性降低,血栓中胶原含量增加,血栓的体积增大,其溶解受到明显抑制。 因此我们设想,若能主动增强静脉血栓中单核细 …