G1/S-specific cyclin-D2 is a protein that in humans is encoded by the CCND2 gene. [5] The protein encoded by this gene belongs to the highly conserved cyclin family, whose members …

Mar 30, 2025 · CCND2 (Cyclin D2) is a Protein Coding gene. Diseases associated with CCND2 include Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 3 and …

The CCND2 gene provides instructions for making a protein called cyclin D2. Learn about this gene and related health conditions.

Chromosome 12: 4,382,938-4,414,516 forward strand. This gene has 4 transcripts (splice variants), 10 paralogues and is associated with 62 phenotypes. Sorry, the page request …

Sep 3, 2020 · HGNC Approved Gene Symbol: CCND2. Cytogenetic location: 12p13.32 Genomic coordinates (GRCh38) : 12:4,273,762-4,305,353 (from NCBI) Inaba et al. (1992) used murine …

Feb 21, 2013 · Chromosomal rearrangements of the CCND2 locus were detected in 55% of the cases, with an IG gene as partner in 18 of 22, in particular with light chains (10 IGK@ and 5 …

CCND2 Gene: 894: Uniprot Function: Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including …

• CCND2 was significantly lower in lung adenocarcinoma (LUAD) than adjacent normal tissues. • LUAD patients who expressed lower CCND2 had a shorter overall survival and CCND2 was …

Dec 2, 2016 · CCND2 is a cell cycle regulator whose activity is dependent on its binding to CDK4/6 in G1 phase. Phosphorylation of Rb (Retinoblastoma), by CDK4/6-CCND2, uncouples …

Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 …