The CCND1 gene encodes the cyclin D1 protein. The human CCND1 gene is located on the long arm of chromosome 11 (band 11q13). It is 13,388 base pairs long, and translates into 295 …

2025年3月30日 · CCND1 (Cyclin D1) is a Protein Coding gene. Diseases associated with CCND1 include Von Hippel-Lindau Syndrome and Myeloma, Multiple. Among its related pathways are …

Cyclin D1 is a 36-kDa protein encoded by CCND1 gene, located on chromosome 11q13. Cyclin D1 is expressed by the majority of normal human cells apart from cells derived from bone …

2025年2月9日 · CCND1 mutations increase protein stability and promote ibrutinib resistance in mantle cell lymphoma. Mohanty A, et al. Oncotarget, 2016 Nov 8. PMID 27713153, Free PMC …

2016年5月16日 · Cyclin D1 (Ccnd1) together with its binding partner Cdk4 act as a transcriptional regulator to control cell proliferation and migration, and abnormal Ccnd1·Cdk4 expression …

2020年8月10日 · Cyclin D1 (CCND1) amplification relevant to malignant biological behavior exists in solid tumors. The prevalence and utility of CCND1 amplification as a biomarker for the …

CCND1 is associated with cancer development and is frequently overexpressed in various human cancer cells and tissues, including gastric cancer [20, 21]. As an oncogene that promotes cell …

2025年1月5日 · Clinical resource with information about CCND1, A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and …

Cyclin D1 (CCND1) is a core cell cycle regulator and is frequently overexpressed in human cancers, often via amplification, translocation or post-transcription regulation. Accumulating …

2025年2月9日 · Atox1-cyclin D1 loop activity is critical for survival of tumor cells with inactivated TP53. MAT1A activation of glycolysis to promote NSCLC progression depends on stabilizing …