2024年8月28日 · Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder caused by the accumulation of cerebral amyloid-β (Aβ) in the tunica media and adventitia of leptomeningeal and cortical vessels of the brain. The resultant vascular fragility tends to manifest in normotensive elderly patients as lobar intracerebral hemorrhage.

2024年12月1日 · Overall, MRI is the modality of choice in assessing patients with suspected inflammatory cerebral amyloid angiopathy as it is able to visualize the characteristic microhemorrhages and cortical superficial siderosis of cerebral amyloid angiopathy.

2024年8月1日 · The Boston criteria 2.0 were proposed in 2022 in order to better include leptomeningeal and white matter characteristics into the diagnoses of probable and possible cerebral amyloid angiopathy (CAA) 1.

Cerebral amyloid angiopathy-related inflammation (CAA-RI) is a rare but increasingly recognized subtype of CAA. CAA-RI consists of two subtypes: inflammatory cerebral amyloid angiopathy and amyloid β (Aβ)-related angiitis. Acute or subacute onset of cognitive decline or behavioral changes is the most common symptom of CAA-RI.

2023年6月5日 · Cerebral amyloid angiopathy (CAA) is a type of cerebrovascular disorder characterized by the accumulation of amyloid beta-peptide within the leptomeninges and small/medium-sized cerebral blood vessels. The amyloid deposition results in fragile vessels that may manifest in lobar intracerebral hemorrhages (ICH).

2006年9月1日 · Cerebral amyloid angiopathy (CAA) is an important but underrecognized cause of cerebrovascular disorders that predominantly affect elderly patients. CAA results from deposition of β-amyloid protein in cortical, subcortical, and leptomeningeal vessels.

The identification at initial MRI of diffuse cortical and subcortical microhemorrhages in a distribution typical of CAA in elderly patients presenting with infiltrative white matter process or prominent leptomeningeal enhancement is highly suggestive of vascular inflammatory CAA.

淀粉样脑血管病（cerebral amyloid angiopathy，CAA）是老年人自发性脑出血的主要原因之一。 其早期临床症状不易被察觉，多数患者因脑出血入院，且CAA相关脑出血复发率高 [ 1 ] ，所以早诊断、早预防对患者预后尤为重要。

The MRI features of CAA-ri include bilateral and asymmetrical cortical and subcortical white matter vasogenic edema, associated with diffuse CMBs and/or CSS, mainly involving the temporal and parietal lobes, with a great prevalence of micro-hemorrhages in the area of cerebral vasogenic edema.

2018年1月15日 · CAA indicates cerebral amyloid angiopathy; CMB, cerebral microbleed; cSS, cortical superficial siderosis; CT, computed tomography; ICH, intracerebral hemorrhage; and MRI, magnetic resonance imaging.