2021年7月6日 · Lower-than-normal complement C4 values could indicate: – bacterial infections. – hepatitis. – malnutrition. – rejection of a kidney transplant. – systemic lupus erythematosus, which is an autoimmune disease affecting the skin, joints, kidneys, and other organs.

2024年2月25日 · There are several reasons why you might have high complement C4 levels over 45 milligrams per deciliter. If you have had a recent injury or infection, you’re likely to have more C4 in your blood....

2024年10月24日 · What do high levels of C4 mean? High C4 protein levels may mean you’re recovering from an infection or illness. If you’re getting treatment for an autoimmune disease, high C4 typically means treatment is working. High C4 levels may also be a sign of the following health conditions: Ulcerative colitis. Sarcoidosis (inflammatory disease).

What does it mean if your Complement C4a result is too high? Elevation of C4a levels is not predictive of any specific disease. Complement C4a levels can become increased in any condition associated with inflammation.

2022年12月15日 · Complement C4 is a protein that is important for your immune function. It helps clear infections and protects against autoimmunity. Low levels may point to autoimmune disease, including lupus. High levels are rare, poorly understood, and may signal inflammation. Read on to find out more about the C4 test. What is Complement C4? Overview

2019年7月3日 · The complement component 4 (C4) assay is a test used to detect the quantity of C4 complements present in human serum or plasma. Know what are the conditions caused by high complement c4 levels and even get the interpretation of results

Complement C4 is the most polymorphic protein in complement system. A plethora of research data demonstrated that individuals with C4 deficiency are prone to microbial infections and autoimmune disorders. In this review, we will discuss the diversity of complement C4 proteins and its genetic structures.

What does it mean if your C4a Level by RIA result is too high? Elevated levels of C4a, a fragment of the complement protein C4, can be a sign of increased immune system activity, often occurring in response to inflammation, infection, or autoimmune disorders.

Symptoms of high levels of Complement C4a could include fatigue, joint pain, skin rashes, fever, or unexplained weight loss. However, these symptoms can vary widely depending on the underlying condition causing the elevated C4a levels.

2017年12月15日 · There are three general pathways by which the body increases C4a: The Alternative Pathway, The Lectin Pathway, and The Classical Pathway. These pathways are activated by infections, which include bacteria, fungi, viruses, and parasites. Immunoglobulins (IgG, IgM) and CRP can also increase C4a (they can be high in infections).