C3a receptor - Wikipedia
The C3a receptor also known as complement component 3a receptor 1 (C3AR1) is a G protein-coupled receptor protein involved in the complement system. [5][6] The receptor binds to …
C3AR1 Gene - GeneCards | C3AR Protein | C3AR Antibody
2025年3月28日 · C3AR1 (Complement C3a Receptor 1) is a Protein Coding gene. Diseases associated with C3AR1 include Atypical Hemolytic-Uremic Syndrome and Prostate Cancer. …
Revealing the signaling of complement receptors C3aR and C5aR1 …
2023年5月11日 · The complement receptors C3aR and C5aR1, whose signaling is selectively activated by anaphylatoxins C3a and C5a, are important regulators of both innate and …
Nature子刊：徐华强/庄友文团队揭示过敏毒素识别补体受体系统的 …
2023年5月17日 · C3aR，C5aR1和C5aR2三种补体受体均属于Class A类GPCR，构成GPCR超家族中的补体受体亚家族。 C5aR1（CD88）和C5aR2（C5L2或GPR77）为C5aR的两种亚 …
The C3-C3aR axis modulates trained immunity in alveolar …
2025年3月31日 · Inhibiting C3aR, both pharmacologically and with a genetic C3aR knockout, prevented this restoration, indicating the necessity of C3aR engagement. Mechanistically, …
The Complement Receptors C3aR and C5aR Are a New Class of …
2019年7月19日 · Recent studies demonstrate that the complement receptor C3aR and C5aR function as a new class of immune checkpoint receptors. Complement signaling through C3aR …
Cell：从结构上揭示补体受体激活和信号转导耦合机制 - 知乎
补体系统是人体先天性免疫反应的重要组成部分，而 补体级联反应 （complement cascade）的最终产物--- 过敏毒素 C3a 和 C5a. 在人体抵御有害入侵者的复杂过程中，补体系统发挥着关键 …
Complement C3aR signaling: Immune and metabolic modulation …
2024年5月22日 · In this review, we highlight our current understanding of one of the complement proteins, the complement C3a receptor (C3aR), in Alzheimer's disease. We will first describe …
These structures, combined with mutagenesis analysis, reveal a conserved recognition pattern of anaphylatoxins to the complement receptors that is diferent from chemokine receptors, unique …
补体 C3a 受体 1（C3AR1）基因 - MCE
C3a 是一种在补体系统激活过程中释放的过敏毒素。 该基因编码的蛋白质是 C3a 的孤儿 G 蛋白偶联受体。 编码受体与 C3a 的结合激活趋化性、颗粒酶释放、超氧阴离子产生和细菌调理作用 …