Nebulized budesonide has been long used in chronic obstructive pulmonary disease (COPD) exacerbation. This study aimed to compare the effectiveness of nebulized budesonide (NB) versus oral prednisolone (OP) in increasing peak expiratory flow rate (PEFR) of COPD patients in emergency department (ED).

Budesonide for inhalation (brand name, Pulmicort; AstraZeneca) is a corticosteroid used to prevent breathing difficulties, chest tightness, wheezing, and coughing caused by respiratory disorders, such as asthma and COPD. Corticosteroids work because they reduce swelling and irritation in the airways, making air flow easier in the lungs.

2023年8月28日 · Two inhalations of budesonide 160/formoterol 4.5 mcg from a metered-dose inhaler are used in the maintenance treatment of airway obstruction and reducing exacerbations in patients with chronic bronchitis and/or emphysema …

2020年10月28日 · This study aimed to compare the effectiveness of nebulized budesonide (NB) versus oral prednisolone (OP) in increasing peak expiratory flow rate (PEFR) of COPD patients in emergency department (ED). Methods: Patients with COPD exacerbation, referring to ED were enrolled in this randomized trial study.

Inhaled corticosteroids are used in the treatment of chronic obstructive pulmonary disease (COPD) to reduce cough, mucus secretion and airway inflammation. Although their benefit is well...

Clinical studies have suggested nebulized budesonide (NB) as an alternative to systemic corticosteroids for patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). However, the optimal budesonide dose for AECOPD remains ...

Recommendation 2: The AAFP recommends that clinicians prescribe corticosteroids for adults with acute exacerbations of COPD to reduce clinical failure (weak recommendation, low quality of...

Pulmicort (Budesonide) It’s an inhaled steroid. It's the only inhaled steroid available as a solution. Some people with COPD have a hard time generating enough flow to actuate inhalers. For this reason, Pulmicort is a nice option for some people with COPD. The medicine lasts 12 hours, so the recommended dose is one treatment twice daily.

We hypothesized that treatment with high-dose inhaled budesonide would improve clinical symptoms and pulmonary function in subjects with COPD, and that the response to inhaled beta 2-agonist will serve to individualize steroid responders.

Nebulized budesonide may be an alternative to parental/oral prednisolone in the treatment of acute exacerbations of COPD but further studies should be done to evaluate its long-term impact on clinical outcomes after an initial episode of COPD exacerbation.